UniProt Accession

 GSTK1_RAT; P24473; O09034 

Genbank Protein ID

 S83436 

Genbank Nucleotide ID

 AAB50831.1 

Protein Name

 Glutathione S-transferase kappa 1 

Protein Synonyms/Alias

 GST 13-13; GST class-kappa; GSTK1-1; rGSTK1; Glutathione S-transferase subunit 13 

Gene Name

 Gstk1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
36	YQHLWNIKLKLRPAL	acetylation	[1]
38	HLWNIKLKLRPALLA	acetylation	[1]
49	ALLAGIMKDSGNQPP	acetylation	[1]
68	HKGQYILKEIPLLKQ	acetylation	[1]
74	LKEIPLLKQLFQVPM	acetylation	[1]
85	QVPMSVPKDFFGEHV	acetylation	[1]
93	DFFGEHVKKGTVNAM	acetylation	[1]
116	EQPEMLEKVSRELWM	acetylation	[1]
158	QAQHLLNKISTELVK	acetylation	[1]
165	KISTELVKSKLRETT	acetylation	[1]
177	ETTGAACKYGAFGLP	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Might confer protection against genotoxic and cytotoxic electrophiles in the mitochondrial compartment. 

Sequence Annotation

 REGION 16 18 Glutathione binding.
 REGION 200 201 Glutathione binding.
 BINDING 53 53 Glutathione.
 BINDING 183 183 Glutathione; via amide nitrogen and
 MOD_RES 93 93 N6-acetyllysine (By similarity).  

Keyword

 3D-structure; Acetylation; Complete proteome; Direct protein sequencing; Mitochondrion; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 226 AA 

Protein Sequence

Gene Ontology

 GO:0005743; C:mitochondrial inner membrane; IEA:Compara.
 GO:0005759; C:mitochondrial matrix; IDA:HGNC.
 GO:0005777; C:peroxisome; IEA:Compara.
 GO:0004602; F:glutathione peroxidase activity; IEA:Compara.
 GO:0004364; F:glutathione transferase activity; IEA:EC.
 GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
 GO:0006749; P:glutathione metabolic process; IEA:Compara. 

Interpro

 IPR001853; DSBA-like_thioredoxin_dom.
 IPR014440; HCCAis_GSTk.
 IPR012336; Thioredoxin-like_fold. 

Pfam

 PF01323; DSBA 

SMART

  

PROSITE

  

PRINTS