CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008117
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 60S ribosomal protein L37-A 
Protein Synonyms/Alias
 L43; YL35; YP55 
Gene Name
 RPL37A 
Gene Synonyms/Alias
 RPL35A; YLR185W; L9470.6 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
32RSFHVQKKTCSSCGYubiquitination[1]
43SCGYPAAKTRSYNWGubiquitination[1]
52RSYNWGAKAKRRHTTacetylation[2]
52RSYNWGAKAKRRHTTubiquitination[1]
85FQTGSASKASA****ubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Binds to the 23S rRNA (By similarity). 
Sequence Annotation
 ZN_FING 19 37 C4-type (Potential).
 METAL 19 19 Zinc (By similarity).
 METAL 22 22 Zinc (By similarity).
 METAL 34 34 Zinc (By similarity).
 METAL 37 37 Zinc (By similarity).  
Keyword
 3D-structure; Complete proteome; Cytoplasm; Direct protein sequencing; Metal-binding; Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 88 AA 
Protein Sequence
MGKGTPSFGK RHNKSHTLCN RCGRRSFHVQ KKTCSSCGYP AAKTRSYNWG AKAKRRHTTG 60
TGRMRYLKHV SRRFKNGFQT GSASKASA 88 
Gene Ontology
 GO:0022625; C:cytosolic large ribosomal subunit; TAS:SGD.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
 GO:0003735; F:structural constituent of ribosome; TAS:SGD.
 GO:0002181; P:cytoplasmic translation; TAS:SGD. 
Interpro
 IPR011331; Ribosomal_L37ae/L37e.
 IPR001569; Ribosomal_L37e.
 IPR018267; Ribosomal_L37e_CS.
 IPR011332; Ribosomal_zn-bd_dom. 
Pfam
 PF01907; Ribosomal_L37e 
SMART
  
PROSITE
 PS01077; RIBOSOMAL_L37E 
PRINTS