CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033175
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Lysine-specific demethylase 4C 
Protein Synonyms/Alias
  
Gene Name
 KDM4C 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
25YQLWKQGKDIYTIDHubiquitination[1]
496PLQRLKLKCIFCRHRubiquitination[1, 2]
620IVSRDCLKLGPPAEGubiquitination[1]
638QVKWPDGKLYGAKYFubiquitination[1]
679TLDEELPKRVKARFSubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 743 AA 
Protein Sequence
MVKISMDIFV RKFQPDRYQL WKQGKDIYTI DHTKPTPAST PEVKAWLQRR RKVRKASRSF 60
QCARSTSKRP KADEEEEVSD EVDGAEVPNP DSVTDDLKVS EKSEAAVKLR NTEASSEEES 120
SASRMQVEQN LSDHIKLSGN SCLSTSVTED IKTEDDKAYA YRSVPSISSE ADDSIPLSSG 180
YEKPEKSDPS ELSWPKSPES CSSVAESNGV LTEGEESDVE SHGNGLEPGE IPAVPSGERN 240
SFKVPSIAEG ENKTSKSWRH PLSRPPARSP MTLVKQQAPS DEELPEVLSI EEEVEETESW 300
AKPLIHLWQT KSPNFAAEQE YNATVARMKP HCAICTLLMP YHKPDSSNEE NDARWETKLD 360
EVVTSEGKTK PLIPEMCFIY SEENIEYSPP NAFLEEDGTS LLISCAKCCV RVHASCYGIP 420
SHEICDGWLC ARCKRNAWTA ECCLCNLRGG ALKQTKNNKW AHVMCAVAVP EVRFTNVPER 480
TQIDVGRIPL QRLKLKCIFC RHRVKRVSGA CIQCSYGRCP ASFHVTCAHA AGVLMEPDDW 540
PYVVNITCFR HKVNPNVKSK ACEKVISVGQ TVITKHRNTR YYSCRVMAVT SQTFYEVMFD 600
DGSFSRDTFP EDIVSRDCLK LGPPAEGEVV QVKWPDGKLY GAKYFGSNIA HMYQVEFEDG 660
SQIAMKREDI YTLDEELPKR VKARFSTASD MRFEDTFYGA DIIQGERKRQ RVLSSRFKNE 720
YVADPVYRTF LKSSFQKKCQ KRQ 743 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR002999; Tudor.
 IPR001965; Znf_PHD.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
  
SMART
 SM00249; PHD
 SM00333; TUDOR 
PROSITE
  
PRINTS