UniProt Accession

 AN32B_MOUSE; Q9EST5; B1AVH9; Q566J4 

Genbank Protein ID

 AB025582; AK165807; AL683884; BC003489; BC005628; BC093506 

Genbank Nucleotide ID

 BAB12436.1; BAE38387.1; CAM13790.1; AAH03489.1; AAH05628.1; AAH93506.1 

Protein Name

 Acidic leucine-rich nuclear phosphoprotein 32 family member B 

Protein Synonyms/Alias

 Proliferation-related acidic leucine-rich protein PAL31 

Gene Name

 Anp32b 

Gene Synonyms/Alias

 Pal31 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
101	NLSGNNLKDISTLEP	ubiquitination	[1]
110	ISTLEPLKRLDCLKS	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 

Functional Description

 Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity. Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome (By similarity). 

Sequence Annotation

 REPEAT 18 38 LRR 1.
 REPEAT 43 64 LRR 2.
 REPEAT 65 87 LRR 3.
 REPEAT 89 110 LRR 4.
 DOMAIN 123 161 LRRCT.
 MOD_RES 265 265 Phosphothreonine.  

Keyword

 Alternative splicing; Chaperone; Complete proteome; Leucine-rich repeat; Nucleus; Phosphoprotein; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 272 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IDA:MGI.
 GO:0048839; P:inner ear development; IMP:MGI.
 GO:0060021; P:palate development; IMP:MGI.
 GO:0001944; P:vasculature development; IMP:MGI.
 GO:0021591; P:ventricular system development; IMP:MGI. 

Interpro

 IPR001611; Leu-rich_rpt.
 IPR003603; U2A'_phosphoprotein32A_C. 

Pfam

  

SMART

 SM00446; LRRcap 

PROSITE

 PS51450; LRR 

PRINTS