CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022241
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Adaptin ear-binding coat-associated protein 2 
Protein Synonyms/Alias
 NECAP endocytosis-associated protein 2; NECAP-2 
Gene Name
 NECAP2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
58KGQMAYIKLEDRTSGubiquitination[1]
137KQQCEFAKQAQNPDQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Involved in endocytosis (By similarity). 
Sequence Annotation
 MOTIF 240 243 WXXF motif 1.
 MOTIF 260 263 WXXF motif 2.  
Keyword
 Alternative splicing; Cell membrane; Complete proteome; Cytoplasmic vesicle; Endocytosis; Membrane; Polymorphism; Protein transport; Reference proteome; Repeat; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 263 AA 
Protein Sequence
MEESGYESVL CVKPDVHVYR IPPRATNRGY RAAEWQLDQP SWSGRLRITA KGQMAYIKLE 60
DRTSGELFAQ APVDQFPGTA VESVTDSSRY FVIRIEDGNG RRAFIGIGFG DRGDAFDFNV 120
ALQDHFKWVK QQCEFAKQAQ NPDQGPKLDL GFKEGQTIKL NIANMKKKEG AAGNPRVRPA 180
STGGLSLLPP PPGGKTSTLI PPPGEQLAVG GSLVQPAVAP SSDQLPARPS QAQAGSSSDL 240
STVFPHVTSG KALPHLGQRK EDEALLSWPV FGA 273 
Gene Ontology
 GO:0030125; C:clathrin vesicle coat; ISS:UniProtKB.
 GO:0005905; C:coated pit; ISS:UniProtKB.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0006897; P:endocytosis; ISS:UniProtKB.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR012466; NECAP-1.
 IPR011993; PH_like_dom. 
Pfam
 PF07933; DUF1681 
SMART
  
PROSITE
  
PRINTS