CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011339
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Thiamine transporter 
Protein Synonyms/Alias
  
Gene Name
 THI7 
Gene Synonyms/Alias
 THI10; YLR237W; L8083.2 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
588VHHKNNEKQSSTASEubiquitination[1]
596QSSTASEKAA*****ubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Responsible for intake of thiamine. 
Sequence Annotation
 MOD_RES 560 560 Phosphoserine.  
Keyword
 Complete proteome; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 598 AA 
Protein Sequence
MSFGSKVSRA LRFLEIPVKD RASVSFLKNP DLQPIKSANQ TWGFWSNFAY WGVMSFSVGT 60
WMSASSALGV GLSYPETIGT FIVGDVLTII FTLANSCPGY DWKVGFTLAQ RFVFGIYGSA 120
FGIIIRILMS IVNYGSNAWV GGLCINMILD SWSHHYLHLP NTLSSKVAMT TKELIGFIIF 180
HVLTAFCYLM KPYHMNYILI WSCVATFFSM LGMVIYLAKQ AHGVGELFTS TKSTATGSTK 240
AWAWVYMISY WFGSVSPGST NQSDYSRFGS SNWAIWAGTI CALLIPTTLI PVFGVIGAST 300
CDKLYGEQYW MPMDIFNHWL TTNYSAGARA GAFFCGLSFV LSQMSYTISN CGFASGMDLA 360
GLLPKYVDIK RGALFAACVS WACLPWNFYN SSSTFLTVMS SFGVVMTPII SVMICDNFLI 420
RKRQYSITNA FILKGEYYFT KGVNWRAIVA WVCGMTPGLP GIAWEVNNDY FHNTGIVNFF 480
YGDSFFSFLI SFFVYWGLCL LFPFKITVKH DDKDYYGAFT DEEARKKGMV PYSEISEEEI 540
RAYTLGEGYT TGHEYRPEGS DDEIPELVKT SSENTNEFEI VHHKNNEKQS STASEKAA 598 
Gene Ontology
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005886; C:plasma membrane; IDA:SGD.
 GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
 GO:0015234; F:thiamine transmembrane transporter activity; IMP:SGD.
 GO:0015888; P:thiamine transport; IMP:SGD. 
Interpro
 IPR001248; Cyt_pur_permease.
 IPR012681; NCS1. 
Pfam
 PF02133; Transp_cyt_pur 
SMART
  
PROSITE
  
PRINTS