UniProt Accession

 ADHC1_MYCS2; P0CH36; A0QR97; I7FIW6; Q9AE96 

Genbank Protein ID

 AJ291708; CP000480; CP001663 

Genbank Nucleotide ID

 CAC35017.1; ABK70232.1; AFP37487.1 

Protein Name

 NADP-dependent alcohol dehydrogenase C 1 

Protein Synonyms/Alias

 Ms-ADHC 1 

Gene Name

 adhc1 

Gene Synonyms/Alias

 adh; MSMEG_1037; MSMEI_1007 

Created Date

 July 27, 2013 

Organism

 Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 

NCBI Taxa ID

 246196 

Lysine Modification

Position	Peptide	Type	References
210	TVLSQSLKKMEDGLR	pupylation	[1]

Reference

 [1] Expansion of the mycobacterial "PUPylome".
 Watrous J, Burns K, Liu WT, Patel A, Hook V, Bafna V, Barry CE 3rd, Bark S, Dorrestein PC.
 Mol Biosyst. 2010 Feb;6(2):376-85. [PMID: 20094657] 

Functional Description

 Prefers aldehydes over alcohols. 

Sequence Annotation

 METAL 41 41 Zinc 1; catalytic (By similarity).
 METAL 63 63 Zinc 1; catalytic (By similarity).
 METAL 94 94 Zinc 2 (By similarity).
 METAL 97 97 Zinc 2 (By similarity).
 METAL 100 100 Zinc 2 (By similarity).
 METAL 108 108 Zinc 2 (By similarity).
 METAL 159 159 Zinc 1; catalytic (By similarity).
 CROSSLNK 210 210 Isoglutamyl lysine isopeptide (Lys-Gln)  

Keyword

 Complete proteome; Direct protein sequencing; Isopeptide bond; Metal-binding; NADP; Oxidoreductase; Reference proteome; Ubl conjugation; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 349 AA 

Protein Sequence

Gene Ontology

 GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 

Interpro

 IPR013149; ADH_C.
 IPR013154; ADH_GroES-like.
 IPR002085; ADH_SF_Zn-type.
 IPR002328; ADH_Zn_CS.
 IPR011032; GroES-like.
 IPR016040; NAD(P)-bd_dom. 

Pfam

 PF08240; ADH_N
 PF00107; ADH_zinc_N 

SMART

  

PROSITE

 PS00059; ADH_ZINC 

PRINTS