| Tag | Content |
|---|
| CPLM ID | CPLM-009784 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | 3-isopropylmalate dehydratase small subunit |
Protein Synonyms/Alias | Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase |
Gene Name | leuD |
Gene Synonyms/Alias | Rv2987c; MT3065; MTV012.01c |
Created Date | July 27, 2013 |
Organism | Mycobacterium tuberculosis |
NCBI Taxa ID | 1773 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 154 | ATVVLPFKIDDHSAW | pupylation | [1] |
|
Reference | [1] Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] . Festa RA, McAllister F, Pearce MJ, Mintseris J, Burns KE, Gygi SP, Darwin KH. PLoS One. 2010 Jan 6;5(1):e8589. [ PMID: 20066036] |
Functional Description | Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity). |
Sequence Annotation | CROSSLNK 154 154 Isoglutamyl lysine isopeptide (Lys-Gln) |
Keyword | 3D-structure; Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; Isopeptide bond; Leucine biosynthesis; Lyase; Reference proteome; Ubl conjugation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 198 AA |
Protein Sequence | MEAFHTHSGI GVPLRRSNVD TDQIIPAVFL KRVTRTGFED GLFAGWRSDP AFVLNLSPFD 60
RGSVLVAGPD FGTGSSREHA VWALMDYGFR VVISSRFGDI FRGNAGKAGL LAAEVAQDDV 120
ELLWKLIEQS PGLEITANLQ DRIITAATVV LPFKIDDHSA WRLLEGLDDI ALTLRKLDEI 180
EAFEGACAYW KPRTLPAP 198 |
Gene Ontology | GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro. GO:0005886; C:plasma membrane; IDA:MTBBASE. GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:HAMAP. GO:0040007; P:growth; IMP:MTBBASE. GO:0009098; P:leucine biosynthetic process; IMP:MTBBASE. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |