UniProt Accession

 Q4FK36_MOUSE; Q4FK36 

Genbank Protein ID

 BC131926; CT010216; CH466519 

Genbank Nucleotide ID

 AAI31927.1; CAJ18424.1; EDL28434.1 

Protein Name

 Destrin 

Protein Synonyms/Alias

 Destrin, isoform CRA_a; Dstn protein 

Gene Name

 Dstn 

Gene Synonyms/Alias

 mCG_11495 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
19	CRIFYDMKVRKCSTP	ubiquitination	[1]
44	IFCLSADKKCIVVEE	ubiquitination	[1]
78	FVGMLPEKDCRYALY	ubiquitination	[1]
92	YDASFETKESRKEEL	ubiquitination	[1]
112	APEQAPLKSKMIYAS	ubiquitination	[1]
132	KKKFPGIKHEYQANG	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Actin-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 165 AA 

Protein Sequence

Gene Ontology

 GO:0030864; C:cortical actin cytoskeleton; IDA:MGI.
 GO:0030042; P:actin filament depolymerization; IEA:InterPro.
 GO:0006928; P:cellular component movement; IMP:MGI.
 GO:0000910; P:cytokinesis; IMP:MGI.
 GO:0030836; P:positive regulation of actin filament depolymerization; IMP:MGI. 

Interpro

 IPR002108; Actin-bd_cofilin/tropomyosin.
 IPR017904; ADF/Cofilin/Destrin. 

Pfam

 PF00241; Cofilin_ADF 

SMART

 SM00102; ADF 

PROSITE

 PS51263; ADF_H 

PRINTS

 PR00006; COFILIN.