CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026268
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain, isoform CRA_a 
Protein Synonyms/Alias
 Medium-chain-specific acyl-CoA dehydrogenase, mitochondrial 
Gene Name
 ACADM 
Gene Synonyms/Alias
 hCG_22915 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
69PVAAEYDKTGEYPVPubiquitination[1]
250DPKAPANKAFTGFIVubiquitination[1]
269PGIQIGRKELNMGQRubiquitination[1]
289GIVFEDVKVPKENVLubiquitination[1]
292FEDVKVPKENVLIGDubiquitination[1]
312VAMGAFDKTRPVVAAubiquitination[1]
334RALDEATKYALERKTubiquitination[1]
428EKLMRDAKIYQIYEGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; FAD; Flavoprotein; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 454 AA 
Protein Sequence
MAAGFGRCCR VLRSISRFHW RSQHTKANRQ REPGLGFSFE FTEQQKEFQA TARKFAREEI 60
IPVAAEYDKT GEYPVPLIRR AWELGLMNTH IPENCDYSVC PLLEACTLYL DAFFLLLTGS 120
NLNLHLNLGG LGLGTFDACL ISEELAYGCT GVQTAIEGNS LGQMPIIIAG NDQQKKKYLG 180
RMTEEPLMCA YCVTEPGAGS DVAGIKTKAE KKGDEYIING QKMWITNGGK ANWYFLLARS 240
DPDPKAPANK AFTGFIVEAD TPGIQIGRKE LNMGQRCSDT RGIVFEDVKV PKENVLIGDG 300
AGFKVAMGAF DKTRPVVAAG AVGLAQRALD EATKYALERK TFGKLLVEHQ AISFMLAEMA 360
MKVELARMSY QRAAWEVDSG RRNTYYASIA KAFAGDIANQ LATDAVQILG GNGFNTEYPV 420
EKLMRDAKIY QIYEGTSQIQ RLIVAREHID KYKN 454 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:HPA.
 GO:0003995; F:acyl-CoA dehydrogenase activity; IEA:InterPro.
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. 
Interpro
 IPR006089; Acyl-CoA_DH_CS.
 IPR006092; Acyl-CoA_DH_N.
 IPR006090; Acyl-CoA_Oxase/DH_1.
 IPR006091; Acyl-CoA_Oxase/DH_cen-dom.
 IPR009075; AcylCo_DH/oxidase_C.
 IPR013786; AcylCoA_DH/ox_N.
 IPR009100; AcylCoA_DH/oxidase. 
Pfam
 PF00441; Acyl-CoA_dh_1
 PF02770; Acyl-CoA_dh_M
 PF02771; Acyl-CoA_dh_N 
SMART
  
PROSITE
 PS00072; ACYL_COA_DH_1
 PS00073; ACYL_COA_DH_2 
PRINTS