UniProt Accession

 CLCB_MOUSE; Q6IRU5; Q8BR04; Q8CDX9; Q9CV35 

Genbank Protein ID

 AK009844; AK029382; AK045989; BC070404 

Genbank Nucleotide ID

 BAB26539.1; BAC26430.1; BAC32563.1; AAH70404.1 

Protein Name

 Clathrin light chain B 

Protein Synonyms/Alias

 Lcb 

Gene Name

 Cltb 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
112	KWREEQKKRLQELDA	ubiquitination	[1]
159	INNRIADKAFYQQPD	ubiquitination	[1]
181	ASEEAFVKESKEETP	ubiquitination	[1]
184	EAFVKESKEETPGTE	ubiquitination	[1]
204	QLCDFNPKSSKQCKD	acetylation	[2]
204	QLCDFNPKSSKQCKD	ubiquitination	[1]
223	RSVLMSLKQTPLSR*	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

 Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. 

Sequence Annotation

 REGION 93 155 Involved in binding clathrin heavy chain.
 MOD_RES 11 11 Phosphoserine (By similarity).
 MOD_RES 13 13 Phosphoserine (By similarity).
 DISULFID 199 209 By similarity.  

Keyword

 Alternative splicing; Calcium; Coated pit; Complete proteome; Cytoplasmic vesicle; Disulfide bond; Membrane; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 229 AA 

Protein Sequence

Gene Ontology

 GO:0060170; C:cilium membrane; IDA:MGI.
 GO:0030118; C:clathrin coat; ISS:UniProtKB.
 GO:0030132; C:clathrin coat of coated pit; IEA:InterPro.
 GO:0030130; C:clathrin coat of trans-Golgi network vesicle; IEA:InterPro.
 GO:0005802; C:trans-Golgi network; IDA:MGI.
 GO:0042277; F:peptide binding; IEA:Compara.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; IEA:InterPro. 

Interpro

 IPR000996; Clathrin_L-chain. 

Pfam

 PF01086; Clathrin_lg_ch 

SMART

  

PROSITE

 PS00224; CLATHRIN_LIGHT_CHN_1
 PS00581; CLATHRIN_LIGHT_CHN_2 

PRINTS