CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037442
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 FCH and double SH3 domains protein 2 
Protein Synonyms/Alias
  
Gene Name
 FCHSD2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
66KLASQYLKRDWPGVKubiquitination[1]
123ARTVRSLKEQQLKRCubiquitination[1]
188QSRISLQKASVKLKAubiquitination[1]
350TEEHSLNKEARKWATubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 764 AA 
Protein Sequence
MQPPPRKVKV TQELKNIQVE QMTKLQAKHQ AECDLLEDMR TFSQKKAAIE REYAQGMQKL 60
ASQYLKRDWP GVKADDRNDY RSMYPVWKSF LEGTMQVAQS RMNICENYKN FISEPARTVR 120
SLKEQQLKRC VDQLTKIQTE LQETVKDLAK GKKKYFETEQ MAHAVREKAD IEAKSKLSLF 180
QSRISLQKAS VKLKARRSEC NSKATHARND YLLTLAAANA HQDRYYQTDL VNIMKALDGN 240
VYDHLKDYLI AFSRTELETC QAVQNTFQFL LENSSKVVRD YNLQLFLQEN AVFHKPQPFQ 300
FQPCDSDTSL KAAQLVDIEL SPVSALRMTI AESRQLESET GTTEEHSLNK EARKWATRVA 360
REHKNIVHQQ RVLNDLECHG AAVSEQSRAE LEQKIDEARE NIRKAEIIKL KAEARLDLLK 420
QIGVSVDTWL KSAMNQVMEE LENERWARPP AVTSNGTLHS LNADTEREEG EEFEDNMDVF 480
DDSSSSPSGT LRNYPLTCKV VYSYKASQPD ELTIEEHEVL EVIEDGDMED WVKARNKVGQ 540
VGYVPEKYLQ FPTSNSLLSM LQSLAALDSR SHTSSNSTEA ELVSGSLNGD ASVCFVKALY 600
DYEGQTDDEL SFPEGAIIRI LNKENQDDDG FWEGEFNGRI GVFPSVLVEE LSASENGDTP 660
WMREIQISPS PKPHASLPPL PLYDQPPSSP YPSPDKRSSL YFPRSPSANE KSLHAESPGF 720
SQASRHTPET SYGKLRPVRA APPPPTQNHR RPAEKIEDVE ITLV 764 
Gene Ontology
  
Interpro
 IPR001060; FCH_dom.
 IPR001452; SH3_domain. 
Pfam
 PF00611; FCH
 PF00018; SH3_1 
SMART
 SM00326; SH3 
PROSITE
 PS50133; FCH
 PS50002; SH3 
PRINTS
 PR00452; SH3DOMAIN.