CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015553
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 RNA-binding protein 43 
Protein Synonyms/Alias
 RNA-binding motif protein 43 
Gene Name
 RBM43 
Gene Synonyms/Alias
 C2orf38 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
8MASVLNVKESKAPERubiquitination[1]
44KSHFQDIKNEGGDVEubiquitination[1]
70AYVIFKEKKVAENVIacetylation[2]
71YVIFKEKKVAENVIRacetylation[2]
350LFKKGVMKLIGQKVSubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome.
 Morselli E, Mariño G, Bennetzen MV, Eisenberg T, Megalou E, Schroeder S, Cabrera S, Bénit P, Rustin P, Criollo A, Kepp O, Galluzzi L, Shen S, Malik SA, Maiuri MC, Horio Y, López-Otín C, Andersen JS, Tavernarakis N, Madeo F, Kroemer G.
 J Cell Biol. 2011 Feb 21;192(4):615-29. [PMID: 21339330
Functional Description
  
Sequence Annotation
 DOMAIN 15 104 RRM.  
Keyword
 Complete proteome; Polymorphism; Reference proteome; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 357 AA 
Protein Sequence
MASVLNVKES KAPERTVVVA GLPVDLFSDQ LLAVLVKSHF QDIKNEGGDV EDVIYPTRTK 60
GVAYVIFKEK KVAENVIRQK KHWLARKTRH AELTVSLRVS HFGDKIFSSV NAILDLSVFG 120
KEVTLETLVK DLKKKIPSLS FSPLKPNGRI SVEGSFLAVK RLRESLLARA CSLLEKDRNF 180
TSEERKWNRQ NPQRNLQRSN NSLASVRTLV PETARSGEML VLDTDVFLYL KHKCGSYEST 240
LKKFHILSQE KVDGEITTIC LKSIQVGSQP NNAKHVKELI EEWSHALYLK LRKETFILEG 300
KENREKRMIK RACEQLSSRY LEVLINLYRT HIDIIGSSSD TYLFKKGVMK LIGQKVS 357 
Gene Ontology
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
  
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS