CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027079
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ldhba protein 
Protein Synonyms/Alias
  
Gene Name
 ldhb 
Gene Synonyms/Alias
 ldhba 
Created Date
 July 27, 2013 
Organism
 Xenopus laevis (African clawed frog) 
NCBI Taxa ID
 8355 
Lysine Modification
Position
Peptide
Type
References
82TPTIVADKDYSVTANacetylation[1]
Reference
 [1] A biotin switch-based proteomics approach identifies 14-3-3ΞΆ as a target of Sirt1 in the metabolic regulation of caspase-2.
 Andersen JL, Thompson JW, Lindblom KR, Johnson ES, Yang CS, Lilley LR, Freel CD, Moseley MA, Kornbluth S.
 Mol Cell. 2011 Sep 2;43(5):834-42. [PMID: 21884983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Glycolysis; NAD; Oxidoreductase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 334 AA 
Protein Sequence
MSTVQEKLIT NVCQDKAAKP TNKITIVGVG QVGMACAVSV LLKELADELA LVDILEDKLK 60
GGVMDLQHGS LFLKTPTIVA DKDYSVTANS RIVVVTGGVR QQEGESRLNL VQRNVNVFKF 120
IIPQVVKYSP DCIIIVVSNP VDILTYVTWK LSGLPQHRII GSGTNLDSAR FRHLISEKLG 180
VHPSSCHGFI LGEHGDTSVA VWSGVNVAGV SLQSLKPEIG TDQDSCNWKE VHKKVVDSAY 240
EVIKLKGYTN WAIGFSVAEI VESITKNLGR VHPVSTMVKG MYGIETEVFL SLPRVLNGNG 300
LTSVINQKLK DDEVGQLQKS AETLWGIQKD LKDL 334 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0004459; F:L-lactate dehydrogenase activity; IEA:InterPro.
 GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.
 GO:0006096; P:glycolysis; IEA:UniProtKB-KW. 
Interpro
 IPR001557; L-lactate/malate_DH.
 IPR011304; L-lactate_DH.
 IPR018177; L-lactate_DH_AS.
 IPR022383; Lactate/malate_DH_C.
 IPR001236; Lactate/malate_DH_N.
 IPR015955; Lactate_DH/Glyco_Ohase_4_C.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF02866; Ldh_1_C
 PF00056; Ldh_1_N 
SMART
  
PROSITE
 PS00064; L_LDH 
PRINTS
 PR00086; LLDHDRGNASE.