CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030616
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 36, C3H1 type-like 1 
Protein Synonyms/Alias
 cDNA FLJ42674 fis, clone BRAMY2029988, highly similar to Transcription factor IIIB 90 kDa subunit 
Gene Name
 BRF1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
63EQKKISSKINYSVLRubiquitination[1, 2]
116DPVTSVGKRLRPLVSacetylation[3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 203 AA 
Protein Sequence
MRENAEYLRE QREKEARIAK EKELGIYKEH KPKKSCKRRE PIQASTAREA IEKMLEQKKI 60
SSKINYSVLR GLSSAGGGSP HREDAQPEHS ASARKLSRRR TPASRSGADP VTSVGKRLRP 120
LVSTQPAKKV ATGEALLPSS PTLGAEPARP QAVLVESGPV SYHADEEADE EEPDEEDGEP 180
CVSALQMMGS NDYGCDGDED DGY 203 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006352; P:DNA-dependent transcription, initiation; IEA:InterPro.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; IEA:InterPro.
 GO:0043488; P:regulation of mRNA stability; IEA:Compara. 
Interpro
 IPR011665; BRF1_TBP-bd.
 IPR000812; TFIIB. 
Pfam
 PF07741; BRF1 
SMART
  
PROSITE
  
PRINTS