CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024507
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Putative short-chain dehydrogenase/reductase family 42E member 2 
Protein Synonyms/Alias
  
Gene Name
 SDR42E2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
30KTQAKPTKAARQKVLacetylation[1]
Reference
 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773] 
Functional Description
  
Sequence Annotation
 ACT_SITE 176 176 Proton acceptor (By similarity).
 BINDING 180 180 NAD (By similarity).  
Keyword
 Complete proteome; NAD; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 422 AA 
Protein Sequence
MKSNPPRSSL EACKAAGQAP QQKTQAKPTK AARQKVLVTG GGGYLGFSLG SHLAKSGTSV 60
ILLDRRRPQW ELSPETKFIQ ADVRDEEALY RAFEGVDCVF HVASYGMSGA EKLQKEQIES 120
INVGGTKLVI DVCVRRRVPR LIYTSTVNVA FGGKPIEQGD EDSVPYFPLD EHVDHYSRTK 180
AIADQLTLMA NGMPLPGGGT LRTCVLRPPG IYGPEEQRHL PRVAGHIKKR LFMFRFGDHK 240
ARMNWVHVHN LVQAHVLAAE ALTTAKGYVA SGQAYYINDG ESVNLFEWMA PLFEKLGYSQ 300
PWIQVPTSWV YLTAAVMERL HLALRPICSL PPLLTRSEVR SVAVTHTFQI AKARAQLGYA 360
PDKFRFADAV ELYVQSTTRR PRGSTARTLL RLLLRLLLFL GLLALALHFL GLQPLHAAVE 420
RL 422 
Gene Ontology
 GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
 GO:0006694; P:steroid biosynthetic process; IEA:InterPro. 
Interpro
 IPR002225; 3Beta_OHSteriod_DH/Estase.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF01073; 3Beta_HSD 
SMART
  
PROSITE
  
PRINTS