CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035782
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Myof 
Protein Synonyms/Alias
  
Gene Name
 Myof 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
102QNRSLPYKQISLLNEacetylation[1]
313EDTSSGAKGYMKVSMacetylation[1]
406VEVSFAGKKVCTNIIacetylation[1]
450YDWDRLTKNDVVGTTacetylation[1]
534ELNTFLEKKPPEKKLacetylation[1]
834LGLSAVEKKFNSFAEacetylation[1]
871SGLVGRHKFSDVTGKacetylation[1]
934RYPGGEWKQAEDTYTacetylation[1]
978INRAVDEKGWEYGITacetylation[1]
1143RNLMALDKDSFSDPYacetylation[1]
1352FMKVFLPKEELYMPPacetylation[1]
1464YIQKGYSKLKIYDCEacetylation[1]
1494TFKLYRGKSDENEDPacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2048 AA 
Protein Sequence
MLRVIVESAT NIPKTKFGKP DPIVSVIFKD EKKKTKKVDN ELNPVWNEIL EFDLRGIPLD 60
SSSSLVIVVK DFETIGQNKL IGTATVSLKD LIGDQNRSLP YKQISLLNEK GQDTGATIDL 120
VIGYTPPSAP YPNDPSGTSV TGVGEEEEED QGDEDRVDGM VRGPGPKGPS GTMSEAQLAR 180
RITKGKSSRR MLSNKPQDFQ IRVRVIEGRQ LCGNNIRPVV KVHVCGQTHR TRIKRGNNPF 240
FDELFFYNVH ITPSELMDEI ISIRVYNSHS LRADSLMGEF KIDVGFVYDE PGHAVMRKWL 300
LLNDPEDTSS GAKGYMKVSM FVLGTGDEPP SEKRDRDNDS DDVESNLLLP AGIALRWVTF 360
LLKIYRAEDI PQMDDAFSQT VKEIFGGNAD KKNLVDPFVE VSFAGKKVCT NIIERNANPE 420
WNQVVNLQIK FPSMCEKIKL TVYDWDRLTK NDVVGTTYLY LSKIAASGGE VEANTGETEV 480
GFVPTFGPCY LNLYGSPREY TGFPDPYDEL NSGKGEGVAY RGRILVELNT FLEKKPPEKK 540
LEPISNDDLL VVEKYQRRRK YSLSAVFHSA TMLQDVGEAI QFEVSIGNYG NKFDATCKPL 600
ASTTQYSRAV FDGNYYYYLP WARTKPVVTL TSYWEDISHR LDAVNTLLVM AERLQSNIEA 660
VKSGIQGKIP TNQLAELWLK LIDEVIEDTR YTLPVTEGKA NVTVLDTQIR KLRLRFLSQI 720
HEAALRMRSE ATDVKSTLLE IEEWLDKLMQ LTEEPQNSMP DIIIWMIRGE KRLAYARIPA 780
HQVLYSTSGG NASGKYCGKT QTILLKYPQE KNNGPKVPVE LRVNIWLGLS AVEKKFNSFA 840
EGTFTVFAEM YENQALVFGK WGTSGLVGRH KFSDVTGKIK LKREFFLPPK GWEWEGDWVV 900
DPERSLLTEA DAGHTEFTDE VYQNETRYPG GEWKQAEDTY TDANGDKAAS PNEMTCPPGW 960
EWEDDAWTYD INRAVDEKGW EYGITIPPDN KPKSWVAAEK MYHTHRRRRL VRKRKKDLTQ 1020
TASSTARAME ELEDREGWEY ASLIGWKFHW KQRSSDTFRR RRWRRKMAPS ETHGAAAIFK 1080
LEGALGADTT EDGDEKSLEK QKHSATTVFG ANTPIVSCNF DRVYIYHLRC YIYQARNLMA 1140
LDKDSFSDPY AHVSFLHRSK TTEIIHSTLN PTWDQTIIFD DVEIFGEPQT VLQNPPKVII 1200
ELFDSDQVGK DEFLGRSICS PLVKLNSETD TTPKLLWHPV MNGDKACGDV LVTAELILRN 1260
KDGSNLPILP SQRAPNLYMV PQGIRPVVQL TAIEILAWGL RNMKNYQMAS ITSPSLVVEC 1320
GGERVESVVI KSLKKTPNFP SSVLFMKVFL PKEELYMPPL VIKVIDHRQF GRKPVVGQCT 1380
IDHLDRFRCD PYAGKEDIVP QLKASLMSAP PCRDVIIEIE DTKPLLASKL SEKEEEIVDW 1440
WSKFYASSGE HEKCGQYIQK GYSKLKIYDC ELEDVADFEG LTDFSDTFKL YRGKSDENED 1500
PSVVGEFKGS FRIYPLPDDP SVPAPPRQFR ELPDSVPQEC TVRIYIVQGL QLQPQDNNGL 1560
CDPYIKITLG KKVIEDRDHY IPNTINPVFG RMYELSCYLP QEKDLKISVY DYDTFTRDEK 1620
VGETTIDLEN RFLSRFGSHC GIPEQYCVSG VNTWRDQLRP TQLLQNVARF KGFPPPVLSE 1680
DGSRIQYGGR DYHLDEFEAN KILHQHLGAP EERLALHILR TQGLVPEHVE TRTLHSTFQP 1740
NISQGKLQMW VDVFPKSLGP PGPPFNITPR KAKTYYLRVI IWNTRDVILD EKSITGEDMS 1800
DIYVKGWISG SEENKQKTDV HYRSLDGEGN FNWRFVFPFD YLPAEQLCIV AKKEHFWSID 1860
QTEFRVPPRL IIQIWDNDKF SLDDYLGFLE LDLHRTIIPA KTSEKCSLDM IPDLKAMDPL 1920
KAKTASLFEQ KSMKGWWPCY ADKDGSRVMA GKVEMTLEVL NEREADERPA GKGRSEPNMN 1980
PKLDPPNRPE TSFLWFTNPC KTMRFIVWRR FKWVIIGLLL LLILLLFVAV LLYSLPNYLS 2040
MKIVRPNA 2048 
Gene Ontology
 GO:0005901; C:caveola; IEA:Compara.
 GO:0031410; C:cytoplasmic vesicle; IEA:Compara.
 GO:0070062; C:extracellular vesicular exosome; IEA:Compara.
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0043231; C:intracellular membrane-bounded organelle; IEA:Compara.
 GO:0005543; F:phospholipid binding; IEA:Compara.
 GO:0034605; P:cellular response to heat; IEA:Compara.
 GO:0001778; P:plasma membrane repair; IEA:Compara.
 GO:0030947; P:regulation of vascular endothelial growth factor receptor signaling pathway; IEA:Compara. 
Interpro
 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR018029; C2_membr_targeting.
 IPR012968; FerIin-domain.
 IPR012560; Ferlin_A-domain.
 IPR012561; Ferlin_B-domain.
 IPR006614; Peroxin/Ferlin. 
Pfam
 PF00168; C2
 PF08165; FerA
 PF08150; FerB
 PF08151; FerI 
SMART
 SM00239; C2
 SM00694; DysFC
 SM00693; DysFN 
PROSITE
 PS50004; C2 
PRINTS