UniProt Accession

 CHRC1_HUMAN; Q9NRG0 

Genbank Protein ID

 AF226076; AK023537; BC015891 

Genbank Nucleotide ID

 AAF72416.1; BAB14601.1; AAH15891.1 

Protein Name

 Chromatin accessibility complex protein 1 

Protein Synonyms/Alias

 CHRAC-1; Chromatin accessibility complex 15 kDa protein; CHRAC-15; HuCHRAC15; DNA polymerase epsilon subunit p15 

Gene Name

 CHRAC1 

Gene Synonyms/Alias

 CHRAC15 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
102	PKKILASKYLKMLKE	acetylation	[1]

Reference

 [1] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861] 

Functional Description

 Forms a complex with DNA polymerase epsilon subunit POLE3 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome remodeling activity of ISWI/SNF2H and ACF1. 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine.
 MOD_RES 102 102 N6-acetyllysine.
 MOD_RES 124 124 Phosphoserine.  

Keyword

 Acetylation; Coiled coil; Complete proteome; DNA-binding; DNA-directed DNA polymerase; Nucleotidyltransferase; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 131 AA 

Protein Sequence

Gene Ontology

 GO:0008623; C:CHRAC; NAS:UniProtKB.
 GO:0008622; C:epsilon DNA polymerase complex; NAS:UniProtKB.
 GO:0003677; F:DNA binding; NAS:UniProtKB.
 GO:0003887; F:DNA-directed DNA polymerase activity; NAS:UniProtKB.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0006338; P:chromatin remodeling; NAS:UniProtKB. 

Interpro

 IPR003958; CBFA_NFYB_domain.
 IPR009072; Histone-fold. 

Pfam

 PF00808; CBFD_NFYB_HMF 

SMART

  

PROSITE

  

PRINTS