UniProt Accession

 YD13A_YEAST; O74302; D6VSP5 

Genbank Protein ID

 Z74387; BK006938 

Genbank Nucleotide ID

 CAA98915.1; DAA12105.1 

Protein Name

 Transposon Ty1-DR4 Gag polyprotein 

Protein Synonyms/Alias

 Gag-p49; Transposon Ty1 protein A; TY1A; TYA; p58; Capsid protein; CA; Gag-p45; p54; Gag-p4 

Gene Name

 TY1A-DR4 

Gene Synonyms/Alias

 YDRCTy1-3 GAG; YDR261C-C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
39	PLDVSASKTEECEKA	acetylation	[1]
39	PLDVSASKTEECEKA	ubiquitination	[2]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity). 

Sequence Annotation

 REGION 299 401 RNA-binding (By similarity).
 MOD_RES 416 416 Phosphoserine (By similarity).  

Keyword

 Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Ribosomal frameshifting; RNA-binding; Transposable element. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 440 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0000943; C:retrotransposon nucleocapsid; ISS:SGD.
 GO:0003723; F:RNA binding; ISS:SGD.
 GO:0032197; P:transposition, RNA-mediated; ISS:SGD. 

Interpro

 IPR015820; Retrotransposon_Ty1A_N. 

Pfam

 PF01021; TYA 

SMART

  

PROSITE

  

PRINTS