CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017934
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 417 
Protein Synonyms/Alias
  
Gene Name
 ZNF417 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
127NRSGACGKNLDDTAYubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 15 88 KRAB.
 ZN_FING 92 114 C2H2-type 1.
 ZN_FING 240 262 C2H2-type 2.
 ZN_FING 268 290 C2H2-type 3.
 ZN_FING 296 318 C2H2-type 4.
 ZN_FING 324 346 C2H2-type 5; degenerate.
 ZN_FING 352 374 C2H2-type 6.
 ZN_FING 380 402 C2H2-type 7.
 ZN_FING 408 430 C2H2-type 8.
 ZN_FING 436 458 C2H2-type 9.
 ZN_FING 464 486 C2H2-type 10.
 ZN_FING 492 514 C2H2-type 11.
 ZN_FING 520 542 C2H2-type 12.
 ZN_FING 548 570 C2H2-type 13.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 575 AA 
Protein Sequence
MAAAAPRRPT QQGTVTFEDV AVNFSQEEWC LLSEAQRCLY RDVMLENLAL ISSLGCWCGS 60
KDEEAPCKQR ISVQRESQSR TPRAGVSPKK AHPCEMCGLI LEDVFHFADH QETHHKQKLN 120
RSGACGKNLD DTAYLHQHQK QHIGEKFYRK SVREASFVKK RKLRVSQEPF VFREFGKDVL 180
PSSGLCQEAA AVEKTDSETM HGPPFQEGKT NYSCGKRTKA FSTKHSVIPH QKLFTRDGCY 240
VCSDCGKSFS RYVSFSNHQR DHTAKGPYDC GECGKSYSRK SSLIQHQRVH TGKTAYPCEE 300
CGKSFSQKGS LISHQRVHTG ERPYECREYG KSFGQKGNLI QHQQGHTGER AYHCGECGKS 360
FRQKFCFINH QRVHTGERPY KCGECGKSFG QKGNLVQHQR GHTGERPYEC KECGKSFRYR 420
SHLTEHQRLH TGERPYNCRE CGKLFNRKYH LLVHERVHTG ERPYACEVCG KLFGNKNCVT 480
IHQRIHTGER PYECNECGKS FLSSSALHVH KRVHSGQKPY KCSECGKSFA ECSSLIKHRR 540
IHTGERPYEC TKCGKTFQRS STLLHHQSSH RRKAL 575 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB
 PF00096; zf-C2H2 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS