CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005143
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 205 kDa microtubule-associated protein 
Protein Synonyms/Alias
  
Gene Name
 Map205 
Gene Synonyms/Alias
 CG1483 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
1098APGKAASKPLTPQSKacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
 May play an important role in the regulation of microtubule assembly and interaction. 
Sequence Annotation
 REGION 745 977 Microtubule-binding (Potential).
 MOD_RES 354 354 Phosphoserine.
 MOD_RES 448 448 Phosphoserine.
 MOD_RES 450 450 Phosphotyrosine.
 MOD_RES 709 709 Phosphoserine.
 MOD_RES 710 710 Phosphoserine.
 MOD_RES 712 712 Phosphoserine.
 MOD_RES 721 721 Phosphothreonine.
 MOD_RES 728 728 Phosphoserine.
 MOD_RES 874 874 Phosphoserine.
 MOD_RES 1075 1075 Phosphoserine.
 MOD_RES 1086 1086 Phosphoserine.
 MOD_RES 1121 1121 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1185 AA 
Protein Sequence
MEHHEDNAQL DNYLQNRLAE SLQICGGAGE HNPHLADATG GNGCAPGIAP SKSDEVDGEE 60
DEEWKYIHEV RQSEKLQQEK LPLTKETGNG FGPGRDSDNQ VHGNGAAAVF NLYEEDVEVI 120
KNDGDFSTNS NTTTSTDEVV ARQAQEPNQL PEQLQQQQQI ESQGVHEDPR QEDEDEHSSV 180
ATTYGTSSLS ENNSSPLDQE EVVMVAQTVG QEQLVDFDNK ENSYFVKNLE ENHSQLNPNA 240
VAFVPGVGSQ SSSPLPAAED PLPGVQPRPF LPGGTLDDLV AESPRKEFAR INMDGIAVPD 300
EREFDIEADM RPHELEQESD TFGAGHLEMQ LLNGIGTADQ AALRDVLDHG PETSVDMELP 360
LDQVPNDADI MKQSIYAEHN SSIEDILNSV QPLPIQTCDD KELIHVEEKE HVSKSPSTEE 420
LQFQSDFPNN QESHTLFNNT EQDPMQASFY LEHTSQKAQE GCQEQMQLPA ECSDIFADQS 480
LLLDTSAPQL SSEADSPVAK LELESQQAGI VDITPSPLSS TAEKHLVEDT KELVEEYTLD 540
PESHFFGVVS SQAPLQLFGK HTLPSIIHSC KHRVASEQND EENAVFESVS GYETQNFDEI 600
SSPPEGINPF AQPFTPAHLV IEQANTMMED VGGMPIPASE DFAICDKVAS KSSNEVEDHR 660
SEQQAFVKEE LLHPVGDVVA QVENLGTEKN FVVEEERLPI SVSDEIPLSS ASKEKLLPDT 720
TDEQLLTSAL EEKLRSVAPE ESVSTAADGQ SISQFDEYVI ASNKPLEDIL EPEKDVEVAK 780
SLSEKTSVAT VAGGAVVGAT KTHSATKAGS TAASAKSKTE TLVMKKTTAS STSVYGANKS 840
AAPRPSTARL GIKSTSIATK TSTTSSLTGN PRKSLSSNVG STVKPPTKLS GTRPATAPVS 900
KVTLGAKTIT NKPTASGTAS DNVTRTTLRP LVSTNARRPA TSGTGSVASS TARRPVTNAK 960
GSAPGSAAST KVRPAATMTA PVKPKVLSPR STISSTTTVR KVPSTSTPSF STRSPNKQQS 1020
NGLGKNTSST TTSTATATIT KSFTARSAPK FTHSASLTYN NGSTSRRLLV PGSSSTTTTS 1080
SLRKSSPLKA APGKAASKPL TPQSKDGTAK SSPAVLKARN STLMGGEGVA PSNECVPTPN 1140
GQINAEEVVK LKGKGLAEEV KIIEEQKLHE QDVPAHNAEV PLLDF 1185 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005875; C:microtubule associated complex; IDA:FlyBase.
 GO:0030496; C:midbody; IDA:FlyBase.
 GO:0005819; C:spindle; IDA:FlyBase.
 GO:0008017; F:microtubule binding; ISS:FlyBase.
 GO:0051297; P:centrosome organization; IMP:FlyBase.
 GO:0000278; P:mitotic cell cycle; IMP:FlyBase. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS