CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025843
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 variant 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
130GDRSGFGKFERGGNSubiquitination[1]
276NGRYGRRKQYPISLVubiquitination[1]
347VDMMERGKIGLDFCKubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Helicase; Hydrolase; Nucleotide-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 674 AA 
Protein Sequence
QRKTPSSRYS SGMSHVAVEN ALGLDQQFAG LDLNSSDNQS GGSTASKGRY IPPHLRNREA 60
TKGFYDKDSS GWSSSKDKDA YSSFGSRSDS RGKSSFFSDR GSGSRGRFDD RGRSDYDGIG 120
SRGDRSGFGK FERGGNSRWC DKSDEDDWSK PLPPSERLEQ ELFSGGNTGI NFEKYDDIPV 180
EATGNNCPPH IESFSDVEMG EIIMGNIELT RYTRPTPVQK HAIPIIKEKR DLMACAQTGS 240
GKTAAFLLPI LSQIYSDGPG EALRAMKENG RYGRRKQYPI SLVLAPTREL AVQIYEEARK 300
FSYRSRVRPC VVYGGADIGQ QIRDLERGCH LLVATPGRLV DMMERGKIGL DFCKYLVLDE 360
ADRMLDMGFE PQIRRIVEQD TMPPKGVRHT MMFSATFPKE IQMLARDFLD EYIFLAVGRV 420
GSTSENITQK VVWVEESDKR SFLLDLLNAT GKDSLTLVFV ETKKGADSLE DFLYHEGYAC 480
TSIHGDRSQR DREEALHQFR SGKSPILVAT AVAARGLDIS NVKHVINFDL PSDIEEYVHR 540
IGRTGRVGNL GLATSFFNER NINITKDLLD LLVEAKQEVP SWLENMAYEH HYKGSSRGRS 600
KSSRFSGGFG ARDYRQSSGA SSSSFSSSRA SSSRSGGGGH GSSRGFGGGG YGGFYNSDGY 660
GGNYNSQGVD WWGN 674 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 
Interpro
 IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase.
 IPR000629; RNA-helicase_DEAD-box_CS.
 IPR014014; RNA_helicase_DEAD_Q_motif. 
Pfam
 PF00270; DEAD
 PF00271; Helicase_C 
SMART
 SM00487; DEXDc
 SM00490; HELICc 
PROSITE
 PS00039; DEAD_ATP_HELICASE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER
 PS51195; Q_MOTIF 
PRINTS