CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034082
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 UDP-glucose 6-dehydrogenase 
Protein Synonyms/Alias
  
Gene Name
 Ugdh 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
6**MVEIKKICCIGAGacetylation[1]
67VVESCRGKNLFFSTNubiquitination[2]
94ISVNTPTKTYGMGKGubiquitination[2]
107KGRAADLKYIEACARacetylation[1, 3, 4]
107KGRAADLKYIEACARubiquitination[2]
124VQNSNGYKIVTEKSTubiquitination[2]
129GYKIVTEKSTVPVRAacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [4] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 157 AA 
Protein Sequence
MVEIKKICCI GAGYVGGPTC SVIAHMCPEI RVTVVDVNEA RINAWNSPTL PIYEPGLKEV 60
VESCRGKNLF FSTNIDDAIR EADLVFISVN TPTKTYGMGK GRAADLKYIE ACARRIVQNS 120
NGYKIVTEKS TVPVRAAESI RRIFDANTKP NLNLQVL 157 
Gene Ontology
 GO:0051287; F:NAD binding; IEA:InterPro.
 GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
 GO:0001702; P:gastrulation with mouth forming second; IMP:MGI. 
Interpro
 IPR016040; NAD(P)-bd_dom.
 IPR001732; UDP-Glc/GDP-Man_DH_N. 
Pfam
 PF03721; UDPG_MGDP_dh_N 
SMART
  
PROSITE
  
PRINTS