CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015488
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative zinc finger protein 730 
Protein Synonyms/Alias
  
Gene Name
 ZNF730 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
260EKPYQCEKCGKFFNQubiquitination[1]
304SNLTEHKKIHTKEQPubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 May be involved in transcriptional regulation (By similarity). 
Sequence Annotation
 DOMAIN 4 75 KRAB.
 ZN_FING 145 167 C2H2-type 1; degenerate.
 ZN_FING 173 195 C2H2-type 2.
 ZN_FING 228 250 C2H2-type 3.
 ZN_FING 256 278 C2H2-type 4.
 ZN_FING 284 306 C2H2-type 5.
 ZN_FING 312 334 C2H2-type 6.
 ZN_FING 340 362 C2H2-type 7.
 ZN_FING 368 390 C2H2-type 8; degenerate.
 ZN_FING 396 418 C2H2-type 9.
 ZN_FING 424 446 C2H2-type 10.
 ZN_FING 452 474 C2H2-type 11.
 ZN_FING 480 502 C2H2-type 12.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 503 AA 
Protein Sequence
MGALTFRDVA IEFSLEEWQC LDTEQQNLYR NVMLDNYRNL VFLGIAVSKP DLITCLEQEK 60
EPWNLKTHDM VAKPPVICSH IAQDLWPEQG IKDYFQEVIL RQYKKCRHEN LLLRKGCKNV 120
DEFKMHKKGY NRHNQCLTTS HSKIFQCDKY VKVFHKFSNS NRHKIRHTSK KPFKCKECGK 180
LFCILSHLAQ HKKIHTGEKS YKCEEYGKAF NESSNCTTHK RITEKKPYKC KECGKAFNWF 240
SHFTTHKRIH TGEKPYQCEK CGKFFNQSTN LTTHKRIHTG EKPYKCEECG KAFNQSSNLT 300
EHKKIHTKEQ PYKCEKCGKA FKWSSTLTKH KRIHNGEKPY KCEECGKAFN RSSTLNRHKI 360
THTGGKPYKY KECGKAFNQS STLTIHKIIH TVEKFYKCEE CGKAFSRISH LTTHKRIHTG 420
EKPYKCEECG RAFNQSSTLT THKRIHTGEK PYECEECGKA FNRSSTLTTH KIIHSGEKIY 480
KCKECGKAFR RFSHLTRHKT IHT 503 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS