CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026801
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tyrosine recombinase XerC 
Protein Synonyms/Alias
  
Gene Name
 xerC 
Gene Synonyms/Alias
 RPA0182 
Created Date
 July 27, 2013 
Organism
 Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) 
NCBI Taxa ID
 258594 
Lysine Modification
Position
Peptide
Type
References
189PLPIAAAKRLADADEacetylation[1]
Reference
 [1] System-wide studies of N-lysine acetylation in Rhodopseudomonas palustris reveal substrate specificity of protein acetyltransferases.
 Crosby HA, Pelletier DA, Hurst GB, Escalante-Semerena JC.
 J Biol Chem. 2012 May 4;287(19):15590-601. [PMID: 22416131] 
Functional Description
 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity). 
Sequence Annotation
 ACT_SITE 223 223 By similarity.
 ACT_SITE 249 249 By similarity.
 ACT_SITE 317 317 By similarity.
 ACT_SITE 320 320 By similarity.
 ACT_SITE 343 343 By similarity.
 ACT_SITE 352 352 O-(3'-phospho-DNA)-tyrosine intermediate  
Keyword
 Cell cycle; Cell division; Chromosome partition; Complete proteome; Cytoplasm; DNA integration; DNA recombination; DNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 371 AA 
Protein Sequence
MIAASSPRHC EEQSDEAIQR PNALSSWNCF ASLAMTAVAH HPMTDELAMA PSKSAPPPLE 60
LSCAAADLTA EMTKWLSHLR AERRLSGKTL EAYARDVRQF LQFLAGHWGG EVTLGRFARL 120
EATDVRAFMA ARRADEIAGR SLMRALAGMR SFGRFLEREG KGRVGALASV RAPKIKKSLP 180
KPLPIAAAKR LADADERAGE ERETWVLIRD AAVMALLYGS GLRISEALGL KRRDVPAPGK 240
GDTLIVHGKG NKTRMVPVLQ NVLAQIAEYA AACPYNLPPD GPMFVGARGG PLSPRIIQLA 300
MERLRGGLGL PDSATPHALR HSFATHLLSR GGDLRAIQEL LGHASLSTTQ VYTGIDTERL 360
LEVYNSAHPR A 371 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0009037; F:tyrosine-based site-specific recombinase activity; IEA:HAMAP.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0007059; P:chromosome segregation; IEA:HAMAP.
 GO:0006313; P:transposition, DNA-mediated; IEA:HAMAP. 
Interpro
 IPR011010; DNA_brk_join_enz.
 IPR013762; Integrase-like_cat-core.
 IPR002104; Integrase_catalytic.
 IPR010998; Integrase_Lambda-type_N.
 IPR023109; Integrase_recombinase_N.
 IPR004107; Integrase_SAM-like_N.
 IPR023009; Tyrosine_recombinase_XerC/XerD. 
Pfam
 PF02899; Phage_integr_N
 PF00589; Phage_integrase 
SMART
  
PROSITE
  
PRINTS