CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033849
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sec11-like 1 (S. cerevisiae), isoform CRA_d 
Protein Synonyms/Alias
 Signal peptidase complex catalytic subunit SEC11A 
Gene Name
 Sec11a 
Gene Synonyms/Alias
 Sec11l1; mCG_15305 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
114GHIKFLTKGDNNAVDubiquitination[1]
127VDDRGLYKQGQHWLEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Membrane; Protease; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 247 AA 
Protein Sequence
MLSLDFLDDV RRMNKRQLYY QVLNFGMIVS SALMIWKGLM VITGSESPIV VVLSGSMEPA 60
FHRGDLLFLT NRVEDPIRVG EIVVFRIEGR EIPIVHRVLK IHEKQDGHIK FLTKGDNNAV 120
DDRGLYKQGQ HWLEKKDVVG RARGFVPYIG IVTILMNDYP KFKPADPHRA GVDAHVDGYA 180
ITLSGPHLFS VDDTLPSVHL DRLANLLTFV VSLDNLNFIF LSNGHYTSVS AFGEWKTSCS 240
CKRELVH 247 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
 GO:0006465; P:signal peptide processing; IEA:InterPro. 
Interpro
 IPR019758; Pept_S26A_signal_pept_1_CS.
 IPR019756; Pept_S26A_signal_pept_1_Ser-AS.
 IPR019759; Peptidase_S24_S26.
 IPR015927; Peptidase_S24_S26A/B/C.
 IPR011056; Peptidase_S24_S26A/B/C_b-rbn.
 IPR001733; Peptidase_S26B. 
Pfam
 PF00717; Peptidase_S24 
SMART
  
PROSITE
 PS00501; SPASE_I_1
 PS00761; SPASE_I_3 
PRINTS
 PR00728; SIGNALPTASE.