CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006783
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Murein hydrolase activator EnvC 
Protein Synonyms/Alias
 Septal ring factor 
Gene Name
 envC 
Gene Synonyms/Alias
 yibP; b3613; JW5646 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
282YKPTESEKSLMSRTGacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Activator of the cell wall hydrolases AmiA and AmiB. Required for septal murein cleavage and daughter cell separation during cell division. In vitro, exhibits weak endoproteolytic activity on beta-casein. 
Sequence Annotation
  
Keyword
 Cell cycle; Cell division; Coiled coil; Complete proteome; Periplasm; Reference proteome; Signal. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 419 AA 
Protein Sequence
MTRAVKPRRF AIRPIIYASV LSAGVLLCAF SAHADERDQL KSIQADIAAK ERAVRQKQQQ 60
RASLLAQLKK QEEAISEATR KLRETQNTLN QLNKQIDEMN ASIAKLEQQK AAQERSLAAQ 120
LDAAFRQGEH TGIQLILSGE ESQRGQRLQA YFGYLNQARQ ETIAQLKQTR EEVAMQRAEL 180
EEKQSEQQTL LYEQRAQQAK LTQALNERKK TLAGLESSIQ QGQQQLSELR ANESRLRNSI 240
ARAEAAAKAR AEREAREAQA VRDRQKEATR KGTTYKPTES EKSLMSRTGG LGAPRGQAFW 300
PVRGPTLHRY GEQLQGELRW KGMVIGASEG TEVKAIADGR VILADWLQGY GLVVVVEHGK 360
GDMSLYGYNQ SALVSVGSQV RAGQPIALVG SSGGQGRPSL YFEIRRQGQA VNPQPWLGR 419 
Gene Ontology
 GO:0042597; C:periplasmic space; IMP:EcoliWiki.
 GO:0016787; F:hydrolase activity; IDA:EcoliWiki.
 GO:0001896; P:autolysis; IGI:EcoliWiki.
 GO:0000920; P:cytokinetic cell separation; IMP:EcoliWiki.
 GO:0009273; P:peptidoglycan-based cell wall biogenesis; IMP:EcoCyc.
 GO:0042493; P:response to drug; IMP:EcoCyc. 
Interpro
 IPR011055; Dup_hybrid_motif.
 IPR016047; Peptidase_M23. 
Pfam
 PF01551; Peptidase_M23 
SMART
  
PROSITE
  
PRINTS