CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016071
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Hydrocephalus-inducing protein 
Protein Synonyms/Alias
 Protein Hy-3 
Gene Name
 Hydin 
Gene Synonyms/Alias
 Hy3 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
2411PKAGPAAKEEPPLKKacetylation[1]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 5154 AA 
Protein Sequence
MTLKIKCVAN YIKEKIPNVL FLCDPEARLQ QLTASVPLCE QRKYFKQTNK RLEESMGAMH 60
RKMAKVISGL QSKVLPPMSP KVVTEEEVNR MLTPSEFLKE MSLTTEQKLA STRIICRPQI 120
TELLDMGETT HQKFSRVDLD QALFQPFPSE IIFQNYSPCE VYEVPLVLRN NDKIPRMVKV 180
VEESSPYFKI ISPKDIGHKV APGVPSVFRI LFTPEENKDY AHMLTCITER EKFIVPVKAR 240
GARAILDFPD ELNFSTCPVK YNTQKVLLVR NIGNKDSMFH LKTRSPYSVE PTGGILNVGE 300
SMQLEVDFEP QTVGSHDGKL IVTYDTGEMV FVCLYGVAID VNIRLDKNSL IMEKTYISLA 360
NQRSITIHNR TNIIAHFQWK VFATEEEEDK EKYKICDGLN KEEKQETSMI LEDSVLDPSL 420
RERLSIISRT FENQRKLVQG DSMLFLDHVF TIEPPEGDVW PNSSAEITVY FNPLEAKLYQ 480
QTVYCDISGR EIRLPLRIRG EGMGPKLHFN FELLDIGKVF IGSAHCYEAI LSNKGSIDAL 540
FNVIPPTSAL GACFVFNPKE GIIEPSGVQA VQISFSSTIL GYFEEEFLID VNGSPEPVKM 600
TIRGCVIGPT FHFNVPALNF GNVSYGFPHT LMCSLNNTSL VPMTFKLRVR GDGEGMSSIP 660
SYSQESDSKQ WSGINTEMPT TKPKEFTISP NSGTIRAQGF TAIKVTLCSN TVQKYELALV 720
VDVEGIGEEV LALLITARCV VPKLQLVTTE VDFGRCFLKY PYEKTIQLVN HDDLPGCYKV 780
LPQLYENSPP VLLSSPSPCG VISPHSTVSI PLALETQVIG AHRSIVYISV FGSQEAPLAC 840
NIQSIGEGPV IFIHPTQIDF GNIYVLKDTS RILQLSNQSF IPAVFRVRMA NKKSLWTVKP 900
SEGAVPAEDD IPLTLTANLD DIVTFKDTVI LEIKHSNTYR IPIQATGIGS TIVSDKPFAP 960
ELNLGAHFSL DTHYYRFKLT NKGRRVQQLF WMNDDFRPKE KQSKKEPGKK GSTSSSRRQS 1020
KASQEPTDNG NPVFQLYPVR MELYPGQTID VILEGYSATP KKVKEKLVCQ AIVGTQKGKS 1080
LLMSVNIICE FIAPIIQLSA KQLLYRLEKK PNSNLESDYQ SLVIKNITTL PVNMLLSTTR 1140
PFFICETDKS LLPATPKPIK LEVDEEKHLL IKFDPSYRND LNNWVAEEVL SIKYLEHPQV 1200
DNLGLRAEVH YPNLSFEVMD IDFGCILNDT EVIRYIMITN CSPLVVKFRW FFLVDEEENQ 1260
IRFAPCMKPY SAFLSQMESI AATSVTASSL AAPHTVEYTE MDFSDSIKTI LMDDEAGPEE 1320
IKKPATSTMV SEAIKYSSAG TERSQSQPDY PECMWIYEQD EMLSIGIEEV FDILPLYGVL 1380
RPYSSHQISF TFYGHCDIIA RAKALCEVEG GPTYEVLLKG EASLVNYSFD TKDINYGLQL 1440
FDHVTEREIT LKNTGKVGFE FNVLSNYRSS QRNLLPGVPL ILPLSGFIQS NKEQVLKVYY 1500
LPGIPEVFQR NFQIQIAHLV PENITLYGEG IFPRISLDLH RNLQGNEKYE HFLEQAKKNV 1560
EKEYTKYEAV DQYEVMAEEL PEEETAEISA HVQMEVERLI VQDYALEHQR SISNNTEDIY 1620
FSQRSCRKLT KVQLPEYILD FGYIVLGDVR THIVKITNTS HFPVSFHAEK QVLHETGFST 1680
ELDRVKNLPY YETETFEVRC DPQGANLPVG NKEVILPIKV YGGPTIHLCL QATVIIPSMT 1740
LSCNKIEFAT IQCGQCMVET IQLSNHLQVP CEWFVHTPKS TNKLDKHMPK YLRRKLQAEM 1800
IPKSRIFEIQ PTSGILDPGE RANVQVKFMP KEEKLYSQSL LFQIGQSSQK LTLLAQGQGL 1860
EPRLEFSPSV LELGPLLPFA SGDEAEVIVR NPCNFPIEFY SLEFDQQYLL EEKMLRQLKG 1920
YDSYNTLLLP PRNPGEKLPP EVYDYFKEMK KSKEEHMKAK YMENLENEEE EMNTSDQGTT 1980
STKRTSISRG ISVTSNLEER HLTIEAKNYL DEDDYEESLE KLTFQTDKMQ STDSHSVEEV 2040
GEVESNPVSK AIARHLGIDI SAEGRLAKNR KGIAIIVHGT PLSGKTANAI SMAKFYNAAC 2100
LNIDSIVLEA LSDTNNILGI RARELCIRAA IEQSMREAEE SAHESSMTQN TVVPARLSTE 2160
NLGRFTSELT LITQEYKVPK TVRGSVMLPK GKADSHFTGS QKQHHQHQSE TPQVQISSSP 2220
LLPGPTHRRL SVSASIGGET GLMSCVLPDD LLIQILAERI QLSNCFRGVV FDGLDTLFAR 2280
NAPSALHCLL KAIGSREHIY VINMSQDYVV MKAQEKAKKE QEENKRKEAL AKEKERLQTL 2340
DEDEYDALTA EEKVAFDRDV RQALRERKKR ELERLAKEMQ EKKLQQELER QKEEDELKRK 2400
VKRPKAGPAA KEEPPLKKAQ GATNKQLAAV AKIELKMESI ERKVSVREHA TLEETTRKKK 2460
AMTEYPLLIP ISQEQEDSEG DFLKDSDKNL AQKFKIYDMC LKDVQNILMY WDRKQGMMVP 2520
HTGTDEMSHE ADDQRQAPSG GGGRKGRKDR ERERLEKERA EKERLEREKA ERERLEKLKA 2580
LEERSDVEGE GEEEHEGKKD LGVPFINIQS PDFEGVSWKQ ALESDKLPKG DQILDILGLG 2640
SSGPPIPPPV LFSIISYPAK RQSLVATEIL KHFVFVIPPN DDIPLMDEKK DPEGDSDIFL 2700
NTIITKAQEE QPSPPKGSKQ KLKDKPEQVR ETQKEKRRTY SSRKGLPGGT SGSIVPMSDI 2760
DQNSFDGEHS QEKFIRLNHF RWIVPPNGEV TLRVHFSSLD VGNYDQTFNF ELLGTRRQYQ 2820
LYCRGVCTYP YICRDPKVVF SQRKKDMKLK EVVVKKYVVS MEKFYFGPLL CGKSRDKYKS 2880
SLFPGNMETL TILNDSPMVV EAYFCFQHDI KASTYFLEPV NMTLKPNEKQ ALNVWAYPTA 2940
VGIFEDSIVC CIKENPEPAI FKLSCQGIRP EIEVEPRQLH FDRLLLHRKE TKIVILRNVT 3000
PLPVAWRISN LEHLGEDFTV SMMQGTMLPK GEYGLQVHFQ PSKPVNIKKA IRIEVLDAEN 3060
LVGVVQIENI LIFAESYDIA LDITFPKGAE GGLDFGTLRV MEEVKQTLQL KNRGKYEIIF 3120
SFTVDTLGVL PTNLSSMISV QPKRGTLASI DKPTTVQVFF RARKEVKIDC QPILRCQIIE 3180
PTLPEGEIIA SIPIKFSVNA VYSKFTISPS SIINFGALIC GTRKSITFTI ENQGIIDFKY 3240
ALYRLTGESP ILQKKITSHM RHGRTRESES FYKPGATKMA KFSDTVQKDT NIANQARFTH 3300
GMFTVYPGFG SIPSGGQQVI TIECFADPVG RCEEFLAIDI SDRDPRENPA GIPYTLLAEA 3360
CLPAFVTDNN ILIFEEHQIC TSPNLYHILQ TIQSGGLFVE DENKFIFCNV LVGHQAKARF 3420
KISNVGKISC DINIVIKPIS NKPANRITDT FDVEPSKMCI GSRSHAFVTV LFTPQTMQTY 3480
QCIFEATLDG LPSNIARSRG LVFDIVGEGT LPRVTVIRPT LYNQHGNPLL LFKRLLLGHS 3540
EKLPLILKNN GTIPAQLHVD LRDQLGVFSL KGRPTTSYIY IMEENKPNEK VKKAHTASLV 3600
VSPGDTAEFD VFFHSNKIGR MTGTIHLSVI NNQYEETMIH LVGESYEDDI TLDNIHGLIS 3660
STSQESSDKS EVIEIAEEST MEDLVTAALM EHIQFGYCHI GISYNVSFTI TNHSQVNVIR 3720
FEWPLLATLS FSPQIGHLHP GCSKDVVVTL KSESPITLKK MCVKCKLSKI MFQLPVDQVP 3780
DWDDRMRTVK WVDAPRNTPL TLNTKRKVIE MDPEPAHSVV EENYRELRIQ FSANVDFASY 3840
QCETTEVFFK ETLVYQTRVF EFDLVNTGQV LLEFCWISEE ASKAVSFAMP ERQGSSQKEL 3900
SQGSGSSLDS ALDRWTEASP SPFSVEPPSG VVPVGKTQKL KVKFSPMDIG EFESSLYCQI 3960
PNLPLGEQGP ILITKGRSVL PFCHFDLKES DYISGHRRNP ELRGPGAGPL EPNTRVIEFT 4020
SVGIGGKNVQ TFTILNPTNS TYSFCWTSEE TESLQHPPAF VCLTEKGIIH PEKKAEIIFQ 4080
FLPAHLDITE EFWTFSIPEH NISVPFLLVG KTTDPLISLD KSHLNFSSLL IGREARETVK 4140
IINKEEQGFN FAFQDNSRYS EGFNNSLIVC PMEGWIPPLS RFPVDIFFTP KQEGDVNFNL 4200
ICNIKKKAHP LTLNVKAEGY TMNAEVKCRD RMGTTILLTS TQVNTINFYE VELNECVQCE 4260
FSFINTGKFN FSYQAELSGP KLLLQYLDFT PTDSSVDVGQ SEPANLSFQP YQKCVLKGLE 4320
LKIKISHGPT FVCNILGCAV SPAVHFSFTS HNFGTCFIYQ AGMPPYKQIL VVTNKEETSM 4380
SLDCLYTNTP HIEVNFNVDV IKPGKTLEIP ITFYPREAIS YRELIPFEIN GLSQQTVEIK 4440
GKGTEMKLLV LDPANRIVKL GAVLPGQVVR KTVSLVNNSL AQLTFNHSVL FSIPELQEAK 4500
VITLEPFHTI TMKPKEVCKL EITFAPKKRV PPFSEEVFME WMGLLRPLFL LSGCCQALEI 4560
SLDQEHLPFG PVVYQTQATR RILIMNTGDV GARFKWDVKK LKPHFSISPE EGYIISGTEV 4620
ALEVTYHPTE IGKESLYKNI LCFIQGGNPL CLTLSGTCVG PPVVKEVVNF NCQVRSRHTQ 4680
TILLSNRSNQ TWNLHPIFEG EHWEGPEFIT LEAHQQNKPY EITYKPRTMN LENRKHQGTL 4740
FFPLPDGTGW LYALHGTAEL PKAVANIYRE VPCKTPYTEL LPISNWLNKP QRFRVIVEIL 4800
KPEKTDLSVT LKGLDYIDVL SGSKKDYKLN FFSYKEGLYT AKVIFRNEVT NEFLYYTVSF 4860
RVTPSGIIKT IQMTSPVRQS VSASIKLENP LPYSVTFSTE CKLSDISLPS QFAVPPNSEG 4920
TFSFEFQPLK AGELCGRLTL HNSDLGYYQY ELALKALPAP PEKPVHFQTV LGSSQSILAK 4980
FTNYTRLKTE YYCKTDCSDF HTEKVINAAP GAQGGTEVSV EVFFEPSHLG ETKGILCLSS 5040
LIGGEYIIPL FGIALPPKPQ GPFLIRAGYN IIIPFKNVFL HATSFSFIVE NPAFSIRAAE 5100
TVRPKKINNI TVYFEGNPSG SKTPITSKLI VTCPQCEGTE SGIKWVYYLK GITP 5154 
Gene Ontology
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0042384; P:cilium assembly; IMP:MGI.
 GO:0003341; P:cilium movement; IMP:MGI.
 GO:0002064; P:epithelial cell development; IMP:MGI.
 GO:0060438; P:trachea development; IMP:MGI.
 GO:0021591; P:ventricular system development; IMP:MGI. 
Interpro
 IPR008962; PapD-like. 
Pfam
  
SMART
  
PROSITE
  
PRINTS