CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005542
UniProt Accession
Genbank Protein ID
 X64403 
Genbank Nucleotide ID
Protein Name
 CCAAT/enhancer-binding protein gamma 
Protein Synonyms/Alias
 C/EBP gamma 
Gene Name
 Cebpg 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
3*****MSKLSQPASTacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Transcription factor that binds to the promoter and the enhancer of the alpha-1-fetoprotein gene. 
Sequence Annotation
 DOMAIN 62 125 bZIP.
 REGION 66 93 Basic motif (By similarity).
 REGION 97 118 Leucine-zipper (By similarity).  
Keyword
 Activator; Complete proteome; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 150 AA 
Protein Sequence
MSKLSQPAST AGVNGISVIH TQAHASGLQQ VPQLVPAGPG GGGKAVPPSK QSKKSSPMDR 60
NSDEYRQRRE RNNMAVKKSR LKSKQKAQDT LQRVNQLKEE NERLEAKIKL LTKELSVLKD 120
LFLEHAHNLA DNVQPISTET TVANSDNTGQ 150 
Gene Ontology
 GO:0005634; C:nucleus; ISS:UniProtKB.
 GO:0003690; F:double-stranded DNA binding; IDA:RGD.
 GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
 GO:0042803; F:protein homodimerization activity; TAS:RGD.
 GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0008134; F:transcription factor binding; ISS:UniProtKB.
 GO:0030183; P:B cell differentiation; ISS:UniProtKB.
 GO:0043353; P:enucleate erythrocyte differentiation; ISS:UniProtKB.
 GO:0001889; P:liver development; IEP:UniProtKB.
 GO:0016071; P:mRNA metabolic process; IEA:Compara.
 GO:0042267; P:natural killer cell mediated cytotoxicity; ISS:UniProtKB.
 GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
 GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.
 GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; ISS:UniProtKB.
 GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEP:RGD.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR004827; bZIP. 
Pfam
 PF07716; bZIP_2 
SMART
 SM00338; BRLZ 
PROSITE
 PS50217; BZIP
 PS00036; BZIP_BASIC 
PRINTS