UniProt Accession

 SCAR3_HUMAN; Q6AZY7; Q9UM15; Q9UM16 

Genbank Protein ID

 AB007829; AB007830; DQ205185; BC060811; BC075067; BC075068 

Genbank Nucleotide ID

 BAA86201.1; BAA86202.1; ABA27098.1; AAH60811.1; AAH75067.1; AAH75068.1 

Protein Name

 Scavenger receptor class A member 3 

Protein Synonyms/Alias

 Cellular stress response gene protein 

Gene Name

 SCARA3 

Gene Synonyms/Alias

 CSR 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
277	TKTGEAVKNIQATLG	ubiquitination	[1, 2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
 Lee KA, Hammerle LP, Andrews PS, Stokes MP, Mustelin T, Silva JC, Black RA, Doedens JR.
 J Biol Chem. 2011 Dec 2;286(48):41530-8. [PMID: 21987572] 

Functional Description

 Seems to protect cells by scavenging oxidative molecules or harmful products of oxidation. 

Sequence Annotation

 DOMAIN 455 513 Collagen-like 1.
 DOMAIN 544 603 Collagen-like 2.
 CARBOHYD 115 115 N-linked (GlcNAc...) (Potential).
 CARBOHYD 182 182 N-linked (GlcNAc...) (Potential).
 CARBOHYD 224 224 N-linked (GlcNAc...) (Potential).
 CARBOHYD 257 257 N-linked (GlcNAc...) (Potential).
 CARBOHYD 313 313 N-linked (GlcNAc...) (Potential).
 CARBOHYD 337 337 N-linked (GlcNAc...) (Potential).
 CARBOHYD 365 365 N-linked (GlcNAc...) (Potential).
 CARBOHYD 400 400 N-linked (GlcNAc...) (Potential).
 CARBOHYD 430 430 N-linked (GlcNAc...) (Potential).
 CARBOHYD 451 451 N-linked (GlcNAc...) (Potential).  

Keyword

 Alternative splicing; Collagen; Complete proteome; Endoplasmic reticulum; Glycoprotein; Golgi apparatus; Membrane; Polymorphism; Reference proteome; Repeat; Signal-anchor; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 606 AA 

Protein Sequence

Gene Ontology

 GO:0005581; C:collagen; IEA:UniProtKB-KW.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005044; F:scavenger receptor activity; TAS:ProtInc.
 GO:0006979; P:response to oxidative stress; TAS:ProtInc.
 GO:0009650; P:UV protection; TAS:ProtInc. 

Interpro

 IPR008160; Collagen. 

Pfam

 PF01391; Collagen 

SMART

  

PROSITE

  

PRINTS