CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013298
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nucleoporin GLE1 
Protein Synonyms/Alias
 GLE1-like protein 
Gene Name
 Gle1 
Gene Synonyms/Alias
 Gle1l 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
483VQYKLAEKFVKQGEEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC) (By similarity). 
Sequence Annotation
 REGION 1 29 Interaction with NUP155 (By similarity).
 REGION 444 483 Mediates the shuttling between the
 REGION 656 698 Interaction with NUPL2 (By similarity).
 MOD_RES 90 90 Phosphoserine (By similarity).
 MOD_RES 100 100 Phosphoserine (By similarity).  
Keyword
 Coiled coil; Complete proteome; Cytoplasm; mRNA transport; Nuclear pore complex; Nucleus; Phosphoprotein; Protein transport; Reference proteome; Translocation; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 698 AA 
Protein Sequence
MPSDGRCWET LRALRNSSKG RLRYDREWLL RYEDVLEECM SLPKLSSYSG WVVDHILPNT 60
SHHTQENAPS SDNSPSSGSA SGLYQSTLKS PVRSSPQSPS PSTPSGTQSA HESPFTEPIA 120
LQSSRAIKVE GCIRMYELAH RMRGTEGLRQ WQEEQERKVQ ALSEMASEQL KRFDELKELK 180
LHKEFRDLQE VMEKSTREAL GHQEKLKAEH RHRAKILNLK LREAEQQRVK QAEQEQLRKE 240
EGQIRLRSLY TLQEEVLQLN QQLDASSQHK DLLNVDLAAF QTRGNQLCGL ISGIIRTTLE 300
SGYPTAENQA EAERVLQEMR DLLSNLEQEI TRASEMKKKD EEEARVKLQE SQVQQGPGAP 360
TKTSAPSPSL VGTQSEDLQV KVQDSTMQWY QQLQDASAKC VLAFEDLTSS KDSQIKKIKM 420
DLQKAATIPV SQISTIAGSK LKEVFDKIHS LLSGKPVQSG GRSVCVTLNP QGLDFVQYKL 480
AEKFVKQGEE EVASHHEAAF PIAVVASGIW MLHPKVGDLI LAHLHKKCPY SVPFYPAFKE 540
GMPLEDYQRM LGYQVTDSKV EQQDNFLKRM SGMIRLYAAI IQLQWPYGSR QEAHPHGLNH 600
GWRWLAQILN MEPLSDVTAT LLFDFLEVCG NALMKQYQVQ FWKMILLIKE DYFPRIEAIT 660
SSGQMGSFIR LKQFLEKCLQ RREIPVPKGF LTPSFWRS 698 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
 GO:0016973; P:poly(A)+ mRNA export from nucleus; IEA:InterPro.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR012476; GLE1. 
Pfam
 PF07817; GLE1 
SMART
  
PROSITE
  
PRINTS