CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030874
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dpy-30-like protein, isoform CRA_b 
Protein Synonyms/Alias
 Protein dpy-30 homolog; cDNA FLJ58897, moderately similar to Dpy-30-like protein 
Gene Name
 LOC84661 
Gene Synonyms/Alias
 DPY30; hCG_2039808 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
35ERIVENEKINAEKSSacetylation[1, 2, 3]
35ERIVENEKINAEKSSubiquitination[3, 4, 5]
40NEKINAEKSSKQKVDacetylation[3]
45AEKSSKQKVDLQSLPubiquitination[5]
Reference
 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [5] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 120 AA 
Protein Sequence
MEPEQMLEGQ TQVAENPHSE YGLTDNVERI VENEKINAEK SSKQKVDLQS LPTRAYLDQT 60
VVPILLQGLA VLAKERVLQQ RENTAVKYNL KNSANFSQHC FWTFLRVGSG HLQWLNKYHR 120 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
 IPR007858; Dpy-30_motif. 
Pfam
 PF05186; Dpy-30 
SMART
  
PROSITE
  
PRINTS