| Tag | Content |
|---|
| CPLM ID | CPLM-006094 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial |
Protein Synonyms/Alias | Internal NADH dehydrogenase; NADH:ubiquinone reductase (non-electrogenic) |
Gene Name | NDI1 |
Gene Synonyms/Alias | YML120C; YM7056.06C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 418 | AQIPNFQKNLSSRKD | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Catalyzes the oxidation of NADH generated inside the Mitochondrion. |
Sequence Annotation | NP_BIND 55 85 FAD (By similarity).
NP_BIND 229 265 NAD (By similarity). |
Keyword | 3D-structure; Complete proteome; Direct protein sequencing; FAD; Flavoprotein; Membrane; Mitochondrion; Mitochondrion inner membrane; NAD; Oxidoreductase; Reference proteome; Transit peptide; Ubiquinone. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 513 AA |
Protein Sequence | MLSKNLYSNK RLLTSTNTLV RFASTRSTGV ENSGAGPTSF KTMKVIDPQH SDKPNVLILG 60
SGWGAISFLK HIDTKKYNVS IISPRSYFLF TPLLPSAPVG TVDEKSIIEP IVNFALKKKG 120
NVTYYEAEAT SINPDRNTVT IKSLSAVSQL YQPENHLGLH QAEPAEIKYD YLISAVGAEP 180
NTFGIPGVTD YGHFLKEIPN SLEIRRTFAA NLEKANLLPK GDPERRRLLS IVVVGGGPTG 240
VEAAGELQDY VHQDLRKFLP ALAEEVQIHL VEALPIVLNM FEKKLSSYAQ SHLENTSIKV 300
HLRTAVAKVE EKQLLAKTKH EDGKITEETI PYGTLIWATG NKARPVITDL FKKIPEQNSS 360
KRGLAVNDFL QVKGSNNIFA IGDNAFAGLP PTAQVAHQEA EYLAKNFDKM AQIPNFQKNL 420
SSRKDKIDLL FEENNFKPFK YNDLGALAYL GSERAIATIR SGKRTFYTGG GLMTFYLWRI 480
LYLSMILSAR SRLKVFFDWI KLAFFKRDFF KGL 513 |
Gene Ontology | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. GO:0005759; C:mitochondrial matrix; IDA:SGD. GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IDA:SGD. GO:0001300; P:chronological cell aging; IMP:SGD. GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IDA:SGD. GO:0006116; P:NADH oxidation; IDA:SGD. GO:0043065; P:positive regulation of apoptotic process; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |