CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026871
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 L1 cell adhesion molecule 
Protein Synonyms/Alias
 Neural cell adhesion molecule L1 
Gene Name
 L1cam 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1171DSEARPMKDETFGEYubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1259 AA 
Protein Sequence
MVVMLRYVWP LLLCSPCLLI QIPDEYKGHH VLEPPVITEQ SPRRLVVFPT DDISLKCEAR 60
GRPQVEFRWT KDGIHFKPKE ELGVVVHEAP YSGSFTIEGN NSFAQRFQGI YRCYASNKLG 120
TAMSHEIQLV AEGAPKWPKE TVKPVEVEEG ESVVLPCNPP PSAAPLRIYW MNSKILHIKQ 180
DERVSMGQNG DLYFANVLTS DNHSDYICNA HFPGTRTIIQ KEPIDLRVKP TNSMIDRKPR 240
LLFPTNSSSR LVALQGQSLI LECIAEGFPT PTIKWLHPSD PMPTDRVIYQ NHNKTLQLLN 300
VGEEDDGEYT CLAENSLGSA RHAYYVTVEA APYWLQKPQS HLYGPGETAR LDCQVQGRPQ 360
PEITWRINGM SMETVNKDQK YRIEQGSLIL SNVQPSDTMV TQCEARNQHG LLLANAYIYV 420
VQLPARILTK DNQTYMAVEG STAYLLCKAF GAPVPSVQWL DEEGTTVLQD ERFFPYANGT 480
LSIRDLQAND TGRYFCQAAN DQNNVTILAN LQVKEATQIT QGPRSAIEKK GARVTFTCQA 540
SFDPSLQASI TWRGDGRDLQ ERGDSDKYFI EDGKLVIQSL DYSDQGNYSC VASTELDEVE 600
SRAQLLVVGS PGPVPHLELS DRHLLKQSQV HLSWSPAEDH NSPIEKYDIE FEDKEMAPEK 660
WFSLGKVPGN QTSTTLKLSP YVHYTFRVTA INKYGPGEPS PVSETVVTPE AAPEKNPVDV 720
RGEGNETNNM VITWKPLRWM DWNAPQIQYR VQWRPQGKQE TWREQTVSDP FLVVSNTSTF 780
VPYEIKVQAV NNQGKGPEPQ VTIGYSGEDY PQVSPELEDI TIFNSSTVLV RWRPVDLAQV 840
KGHLKGYNVT YWWKGSQRKH SKRHIHKSHI VVPANTTSAI LSGLRPYSSY HVEVQAFNGR 900
GLGPASEWTF STPEGVPGHP EALHLECQSD TSLLLHWQPP LSHNGVLTGY LLSYHPVEGE 960
SKEQLFFNLS DPELRTHNLT NLNPDLQYRF QLQATTQQGP GEAIVREGGT MALFGKPDFG 1020
NISATAGENY SVVSWVPRKG QCNFRFHILF KALPEGKVSP DHQPQPQYVS YNQSSYTQWN 1080
LQPDTKYEIH LIKEKVLLHH LDVKTNGTGP VRVSTTGSFA SEGWFIAFVS AIILLLLILL 1140
ILCFIKRSKG GKYSVKDKED TQVDSEARPM KDETFGEYRS LESDNEEKAF GSSQPSLNGD 1200
IKPLGSDDSL ADYGGSVDVQ FNEDGSFIGQ YSGKKEKEAA GGNDSSGATS PINPAVALE 1259 
Gene Ontology
 GO:0009897; C:external side of plasma membrane; IDA:MGI.
 GO:0042734; C:presynaptic membrane; IDA:MGI.
 GO:0043195; C:terminal bouton; IDA:MGI.
 GO:0042802; F:identical protein binding; IDA:MGI.
 GO:0005178; F:integrin binding; IDA:MGI.
 GO:0033691; F:sialic acid binding; IDA:MGI.
 GO:0007411; P:axon guidance; IDA:MGI.
 GO:0007166; P:cell surface receptor signaling pathway; IDA:MGI.
 GO:0033631; P:cell-cell adhesion mediated by integrin; IMP:MGI.
 GO:0007157; P:heterophilic cell-cell adhesion; IMP:MGI.
 GO:0007156; P:homophilic cell adhesion; IMP:MGI.
 GO:0034109; P:homotypic cell-cell adhesion; IMP:MGI.
 GO:0007159; P:leukocyte cell-cell adhesion; IMP:MGI.
 GO:0050850; P:positive regulation of calcium-mediated signaling; IDA:MGI.
 GO:0022409; P:positive regulation of cell-cell adhesion; IMP:MGI. 
Interpro
 IPR026966; Fibronectin_III_C.
 IPR003961; Fibronectin_type3.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003599; Ig_sub.
 IPR003598; Ig_sub2. 
Pfam
 PF13882; Bravo_FIGEY
 PF00041; fn3
 PF07679; I-set 
SMART
 SM00060; FN3
 SM00409; IG
 SM00408; IGc2 
PROSITE
 PS50853; FN3
 PS50835; IG_LIKE 
PRINTS