| Tag | Content |
|---|
| CPLM ID | CPLM-017460 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | FTS and Hook-interacting protein |
Protein Synonyms/Alias | FHIP; Protein FAM160A2 |
Gene Name | FAM160A2 |
Gene Synonyms/Alias | C11orf56; KIAA1759 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 452 | LYGRAADKFLSLIPR | ubiquitination | [1] | | 847 | KYLIARGKLDWAEGP | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). |
Sequence Annotation | MOD_RES 859 859 Phosphoserine (By similarity).
MOD_RES 897 897 Phosphoserine. |
Keyword | Alternative splicing; Complete proteome; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 972 AA |
Protein Sequence | MERMNWLSRL ASRGPGHRIP QGANLQTPVM ADPETCLMVF KNHWSQVVRI LERQGPRAAP 60
GGADDLSAVR NHTYQMLTLL AEDRAVPSAP TGPGPLLEFA LHEDLLTRVL TWQLQWDELG 120
DGVEERRAEQ LKLFEMLVSE ARQPLLRHGP VREALLTLLD ACGRPVPSSP ALDEGLVLLL 180
SQLCVCVAQE PSLLEFFLQP PPEPGAAPRL LLFSRLVPFV HREGTLGQQA RDALLLLMAL 240
SAGSPTVGRY IADHSYFCPV LATGLSALYS SLPRKIEVPG DDWHCLRRED WLGVPALALF 300
MSSLEFCNAV IQVAHPLVQK QLVDYIHNGF LVPVMGPALH KTSVEEMIAS TAYLELFLRS 360
ISEPALLRTF LRFLLLHRHD THTILDTLVA RIGSNSRLCM VSLSLFRTLL NLSCEDVLLQ 420
LVLRYLVPCN HVMLSQKPAV RDVDLYGRAA DKFLSLIPRC CRHHAPSPPR PEHASWARGG 480
PSRETGRRED ITGPGSPSVD SSSVTTVPRP STPSRLALFL RQQSLGGSES PGPAPCSPGL 540
SASPASSPGR RPTPAEEPGE LEDNYLEYLR EARRGVDRCV RACRTWSAPY DGERPSPEPS 600
PFGSRTKKRS LLPEEDRNNV GEGEEEELGR RGRAGGAGEG PGHLPPPQLN GVPGSWPEGA 660
KKVRLVPKEG AGELLEGISE GMAGLEGFGQ ELRELEVALS NGGTGSESPL EPPLPLEEEE 720
AYESFTCPPE PPGPFLSSPL RTLNQLPSQP FTGPFMAVLF AKLENMLQNS VYVNFLLTGL 780
VAQLACHPQP LLRSFLLNTN MVFQPSVKSL LQVLGSVKNK IENFAASQED FPALLSKAKK 840
YLIARGKLDW AEGPAAGPAP RRSDPLVKSR RPSLGELLLR HAHSPTRARQ AAQLVLQPGR 900
DGAGLGLSGG SPGASTPVLL TRGGAPERQG EALRVKNAVY CAVIFPEFLK ELAAISQAHA 960
VTSPFLLETS EEGSGPLISG CGPLNP 986 |
Gene Ontology | GO:0070695; C:FHF complex; IDA:UniProtKB. GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB. GO:0007032; P:endosome organization; IMP:UniProtKB. GO:0008333; P:endosome to lysosome transport; IMP:UniProtKB. GO:0007040; P:lysosome organization; IMP:UniProtKB. GO:0015031; P:protein transport; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |