CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022805
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein xmas-2 
Protein Synonyms/Alias
  
Gene Name
 xmas-2 
Gene Synonyms/Alias
 CG32562 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
118RNEYGSGKPIKKPQNacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
 Required for spermatogenesis, oogenesis and embryogenesis. 
Sequence Annotation
 DOMAIN 12 83 RRM.  
Keyword
 Complete proteome; Developmental protein; Differentiation; Oogenesis; Reference proteome; RNA-binding; Spermatogenesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1370 AA 
Protein Sequence
MAEPRPGGYN YKTLLCRNIP ELFLDKYVAR SHFGRFGTLV NFVLRPRRMT CTVSYASEDE 60
AARALLDGAS FQGHLFDISY ADNETAPAQK TEEWVDPDIQ AELSALQSGW RNEYGSGKPI 120
KKPQNGSSGS GGSSMLPAIP VGPATAPVSR DRTPAQLRDL ENMMRRPAHT SEEKFSVLDA 180
RDKLLRLNRT QHKLSGATQG HCADMCPEKE RVLREFQRQV AYYELQPGSD ELICHERALK 240
QYSRSSADQE TPLPHELRNE TALHMTMSYL MHEIMDISER QDPQSHMGDW FHFVWDRTRS 300
IRKEITQQEL CSLGAVKLVE QCARFHIHCA ARLVDADPSV FDSKINAENL TKCLQTLKYM 360
YHDLRIKGVP CPKEAEFRGY IVLLNLADAN FLWDIGQLPA ELQSCPEVRQ AIQFYLALQD 420
TNFVRFFQLL ADKDTSYLSA CILVNYFTRL RVLGLHRLIQ AYRSPRKDEV SSLPLSYIAE 480
LLSFASEQEA ADFVQHYGLQ INEAGRVVLS RMHTVETEYK LPRQYELVEV KRVKSVGEVV 540
SGEPLPPRDL YLNHRPHNSF DDYGMLKSIA WTAKDQLAGM QQEEMQPQMP SQPPAVSKHS 600
DTLFKVPMQP DGTAAGFGVF AAAAVPPASS IDGFSFVLPK SRAQEFQEQA PATQQRRAQE 660
EAKHQALQVA IAAAKKREAE LMAIHEAKVA EAERVRQQKL RERQEQQRRQ QQELEEQRQR 720
EQEKLQLEKE RQLKLEQLFF VQQQEREAHK QTRTLELYQE IFQDTLAEIC QSEFMSHSRA 780
CRSYESMLDS ITRDLVERQM EQSIYELGVM RVCIRRWRKY RRTQQEKDTL FNQLPLSFGA 840
ENPEGVVNKR SMEDSLRLSR RYRLGEPCDY GKLLAGLEEH SWLKLDLWHV LDKCLPVAQP 900
GARRFYKLLI SLSGGQEGLQ LNCDLDRGLL QQPQSPDARF VDGGYIRGFS QGIGLSVMKI 960
RDDDHDWKAT DLAEANGIIC LIGLDDIRLL PDRLKPLLQA SRCHDVAVIV QHPANTAFVQ 1020
PDIPLQELCL RSFNIFRLRK SGNNRQRLMI ALESAVKFLA KATERKRVGH LHQVETREYL 1080
LVNLGSELFR RLKYAAEHDT AIRSDTQLNP QRCVDLFNEA VHRLQLVAGE DLSDWPQFPE 1140
ELRVFVQPLP IESSLNTNRL EHFEPGWHLP ERRQRIVQLL ERCKLPKMPV LPRSSSLAEA 1200
QCQWVLDYAQ ISQQEDCVEQ IALQAIKILQ YDTDDYLNFV EYLAGERMQY ILRQERNPPQ 1260
GIVYNTKTLK RRFLSAWYYE FREPQIYEPV PAEENAQMLE KQPSSQAEVQ QLDFDEITSK 1320
AEAVLKRFHQ RQDERHTLRE LNRSHKSRKR RDASDHKHAS KHKRKRSKSK 1370 
Gene Ontology
 GO:0005643; C:nuclear pore; IDA:UniProtKB.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; NAS:UniProtKB.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0009790; P:embryo development; NAS:UniProtKB.
 GO:0007292; P:female gamete generation; NAS:UniProtKB.
 GO:0048477; P:oogenesis; IEA:UniProtKB-KW.
 GO:0016973; P:poly(A)+ mRNA export from nucleus; IMP:FlyBase.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
 GO:0007283; P:spermatogenesis; NAS:UniProtKB. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom.
 IPR005062; SAC3/GANP/Nin1/mts3/eIF-3-p25. 
Pfam
 PF03399; SAC3_GANP 
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS