CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003595
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein-export protein SecB 
Protein Synonyms/Alias
  
Gene Name
 secB 
Gene Synonyms/Alias
 b3609; JW3584 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
19QIQRIYTKDISFEAPacetylation[1]
34NAPHVFQKDWQPEVKacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 One of the proteins required for the normal export of some preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. Its substrates include AmpC, DegP, FhuA, FkpA, GBP, LamB, MalE (MBP), OmpA, OmpF, OmpT, OmpX, OppA, PhoE, TolB, TolC, YbgF, YcgK, YgiW and YncE. 
Sequence Annotation
  
Keyword
 3D-structure; Chaperone; Complete proteome; Cytoplasm; Protein transport; Reference proteome; Translocation; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 155 AA 
Protein Sequence
MSEQNNTEMT FQIQRIYTKD ISFEAPNAPH VFQKDWQPEV KLDLDTASSQ LADDVYEVVL 60
RVTVTASLGE ETAFLCEVQQ GGIFSIAGIE GTQMAHCLGA YCPNILFPYA RECITSMVSR 120
GTFPQLNLAP VNFDALFMNY LQQQAGEGTE EHQDA 155 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0006457; P:protein folding; IEA:HAMAP.
 GO:0006605; P:protein targeting; IMP:EcoliWiki.
 GO:0051262; P:protein tetramerization; IEA:InterPro.
 GO:0043952; P:protein transport by the Sec complex; IMP:EcoliWiki. 
Interpro
 IPR003708; SecB. 
Pfam
 PF02556; SecB 
SMART
  
PROSITE
  
PRINTS
 PR01594; SECBCHAPRONE.