CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037349
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Regulator of G-protein-signaling 9 
Protein Synonyms/Alias
  
Gene Name
 RGS9 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
406DSYARYLKSPIYKDMubiquitination[1]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 628 AA 
Protein Sequence
MTIRHQGQQY RPRMAFLQKI EALVKDMQNP ETGVRMQNQR VLVTSVPHAM TGSDVLQWIV 60
QRLWISSLEA QNLGNFIVRY GYIYPLQDPK NLILKPDGSL YRFQTPYFWP TQQWPAEDTD 120
YAIYLAKRNI KKKGILEEYE KENYNFLNQK MNYKWDFVIM QAKEQYRAGK ERNKADRYAL 180
DCQEKAYWLV HRCPPGMDNV LDYGLDRVTN PNEVKKQTVV AVKKEIMYYQ QALMRSTVKS 240
SVSLGGIVKY SEQFSSNDAI MSGCLPSNPW ITDDTQFWDL NAKLVEIPTK MRVERWAFNF 300
SELIRDPKGR QSFQYFLKKE FSGENLGFWE ACEDLKYGDQ SKVKEKAEEI YKLFLAPGAR 360
RWINIDGKTM DITVKGLKHP HRYVLDAAQT HIYMLMKKDS YARYLKSPIY KDMLAKAIEP 420
QETTKKSSTL PFMRRHLRSS PSPVILRQLE EEAKAREAAN TVDITQPGQH MAPSPHLTVY 480
TGTCMPPSPS SPFSSSCRSP RKPFASPSRF IRRPSTTICP SPIRVALESS SGLEQKGECS 540
GSMAPRGPSV TESSEASLDT SWPRSRPRAP PKARMALSFS RFLRRGCLAS PVFARLSPKC 600
PAVSHGRVQP LGDVGQQLPR LKSKRVAK 628 
Gene Ontology
 GO:0005834; C:heterotrimeric G-protein complex; IEA:InterPro.
 GO:0004871; F:signal transducer activity; IEA:InterPro.
 GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro.
 GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro. 
Interpro
 IPR000591; DEP_dom.
 IPR015898; G-protein_gamma-like_dom.
 IPR000342; Regulat_G_prot_signal.
 IPR024066; Regulat_G_prot_signal_dom1.
 IPR016137; Regulat_G_prot_signal_superfam.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00610; DEP
 PF00631; G-gamma
 PF00615; RGS 
SMART
 SM00049; DEP
 SM00224; GGL
 SM00315; RGS 
PROSITE
 PS50186; DEP
 PS50132; RGS 
PRINTS
 PR01301; RGSPROTEIN.