CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025302
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 Ifit1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
65LAYVRHLKGQQDEALubiquitination[1]
89IQSEQLSKRSLATWGubiquitination[1]
287YQKGLCYKQQISQLRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Repeat; TPR repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 463 AA 
Protein Sequence
MGENADGDQV MENLLQLRCH FTWKLLFENN DIPDLEVRIS EQVQFLDIKN PLGMHNLLAY 60
VRHLKGQQDE ALQSLKEAEA LIQSEQLSKR SLATWGNCAW LHYHRGSLAE AQIYLDKVEK 120
VCKEFSSPFR YRLECAEMDC EEGWALLKCG GGNYKQAMAC FAKALKVEPE NPEYNTGYAV 180
VAYRQDLDDN FISLEPLRKA VRLNPEDPYL KVLLALKLQD LGEHVEAEAH IEEALSSTSC 240
QSYVIRYAAK YFRRKHRVDK ALHLLNRALQ ASPSSGYLHY QKGLCYKQQI SQLRTSRNRQ 300
PRRQDNVQEL AQQAIHEFQE ALKLRPTFEM AYVCMAEVQA EIHQYEEAER NFQKALNNKT 360
LVAHIEQDIH LRYGRFLQFH KQSEDKAITL YLKGLKVEEK SFAWRKLLTA LEKVAERRVC 420
QNVHLVESTS LLGLVYKLKG QEKNALFYYE KALRLTGEMN PAF 463 
Gene Ontology
 GO:0071360; P:cellular response to exogenous dsRNA; IEA:InterPro.
 GO:0035457; P:cellular response to interferon-alpha; IDA:MGI.
 GO:0035458; P:cellular response to interferon-beta; IDA:MGI.
 GO:0071357; P:cellular response to type I interferon; IEA:InterPro.
 GO:0050688; P:regulation of defense response to virus; IEA:InterPro.
 GO:0009615; P:response to virus; IEA:InterPro. 
Interpro
 IPR024121; Interferon-induced_IFIT1.
 IPR001440; TPR-1.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF00515; TPR_1 
SMART
 SM00028; TPR 
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS