Tag | Content |
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CPLM ID | CPLM-011139 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Regulator of V-ATPase in vacuolar membrane protein 2 |
Protein Synonyms/Alias | |
Gene Name | RAV2 |
Gene Synonyms/Alias | YDR202C; YD9346.12C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
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73 | GIPNESNKQNDSPTV | ubiquitination | [1] | 331 | SAKLNSLKASMANHQ | ubiquitination | [1] |
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Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Component of the RAVE complex, which is required for stable assembly of the vacuolar APTase complex V-ATPase under many conditions. May be required for transport between the early endosome and the late endosome/prevacuolar compartment (PVC). |
Sequence Annotation | |
Keyword | Complete proteome; Cytoplasm; Endosome; Membrane; Protein transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 351 AA |
Protein Sequence | MSVDLFPNDR FGAEDKYDNF KDAVKECSWL IEEIVKPQLP NIIDNFSKCL EMLESDQIFK 60 MPVSNGIPNE SNKQNDSPTV KGVITRQGQY IVDFHIVVRF PQFQRGKQVM FRMNTGLNFL 120 LIQFSKIMTH LKNILEILNQ LQVATDVSEF VSKFGVAMEL LNHSLILLQN PPRDLVFPED 180 NNFAMKEMFQ DCYSVCESTA HILGLELTLC RNELCIELRN LIKVTKKPWC EIDSKTGRSF 240 CDQIRNQVTN ERNKTLSKIL SENGVQVQDS TLLNHIISSF QSEAITLPEA QELLRRGVTF 300 DNRVVMECEK LIVSTSDPTL ISISAKLNSL KASMANHQAN LVASKQLSTY K 351 |
Gene Ontology | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. GO:0043291; C:RAVE complex; IPI:SGD. GO:0015031; P:protein transport; IEA:UniProtKB-KW. GO:0043254; P:regulation of protein complex assembly; IMP:SGD. GO:0007035; P:vacuolar acidification; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |