CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028176
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 LD21116p 
Protein Synonyms/Alias
 Tyrosyl-tRNA synthetase 
Gene Name
 Aats-tyr 
Gene Synonyms/Alias
 CG4561; Dmel_CG4561 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
28LGDDKLTKILAERDLacetylation[1]
94SLLELRTKYYEQVIKacetylation[1]
145VVTQHDAKKAGAEVVacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Aminoacyl-tRNA synthetase; Complete proteome; Ligase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 525 AA 
Protein Sequence
MVGITPAEKK ALITRNLQET LGDDKLTKIL AERDLKIYWG TATTGKPHVA YFVPMSKIAD 60
FLKAGCEVTI LFADLHAYLD NMKAPWSLLE LRTKYYEQVI KAMLSSIGVP LEKLKFVKGS 120
DYQLSKEYTL DVYKLSSVVT QHDAKKAGAE VVKQVEYPLL SGLLYPGLQA LDEEYLKVDA 180
QFGGVDQRKI FTFSEKYLPQ LGYEKRIHFM NPMVPGLAGG KMSSSEEDSK IDLLDSPANV 240
KKKLKKAFCE PGNIADNGLL SFVKHVLFSL FKEGEGFEVN REAEHGGDVT FLKYEDLEKY 300
YAEDKLHPGD LKATVEKYIN RLLDPIRKAF ENPELQKLSA AAYPPPAKVK AGAAPAAGAD 360
EDAPHRLDIR VGKVVEVARH PDADTLYVLK IDLAEAQPRT IISGLVKFVT EEELNQRLVA 420
VLCNLKPSKM RGILSEGMVL CTSNADHTVV EPIVLPATAT AGSRLSFEGF SGTPDEQLNP 480
KKKVWEKLSA DFKTNSDGLA VWKDNFLLTP EGEKLSSKLA NCSIK 525 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0000049; F:tRNA binding; IEA:InterPro.
 GO:0004831; F:tyrosine-tRNA ligase activity; IDA:FlyBase.
 GO:0006437; P:tyrosyl-tRNA aminoacylation; IEA:InterPro. 
Interpro
 IPR002305; aa-tRNA-synth_Ic.
 IPR012340; NA-bd_OB-fold.
 IPR014729; Rossmann-like_a/b/a_fold.
 IPR002547; tRNA-bd_dom.
 IPR002307; Tyr-tRNA-ligase.
 IPR023617; Tyr-tRNA-ligase_arc/euk-type. 
Pfam
 PF00579; tRNA-synt_1b
 PF01588; tRNA_bind 
SMART
  
PROSITE
 PS50886; TRBD 
PRINTS
 PR01040; TRNASYNTHTYR.