CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033584
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 CHCHD3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
63SVSDEELKRRVAEELubiquitination[1, 2, 3]
77LALEQAKKESEDQKRubiquitination[2]
141EKDRVLKKQDAFYKEubiquitination[1]
147KKQDAFYKEQLARLEubiquitination[1, 2]
170VTTEQYQKAAEEVEAubiquitination[1, 2, 3]
178AAEEVEAKFKRYESHubiquitination[2, 3]
180EEVEAKFKRYESHPVubiquitination[2]
194VCADLQAKILQCYREubiquitination[1, 3, 4, 5]
230AKQSMLEKGG*****ubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [5] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 232 AA 
Protein Sequence
MGGTTSTRRV TFEADENENI TVVKGIRLSE NVIDRMKESS PSGSKSQRYS GAYGASVSDE 60
ELKRRVAEEL ALEQAKKESE DQKRLKQAKE LDRERAAANE QLTRAILRER ICSEEERAKA 120
KHLVSIKNAR QLEEKDRVLK KQDAFYKEQL ARLEERSSEF YRVTTEQYQK AAEEVEAKFK 180
RYESHPVCAD LQAKILQCYR ENTHQTLKCS ALATQYMHCV NHAKQSMLEK GG 232 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:HPA. 
Interpro
 IPR007964; DUF737. 
Pfam
 PF05300; DUF737 
SMART
  
PROSITE
  
PRINTS