UniProt Accession

 GTPB6_HUMAN; O43824; Q53F77; Q5HYX8 

Genbank Protein ID

 AC126759; BX000483; AK223412; BC014636; BT007360; Y14391 

Genbank Nucleotide ID

 CAI41972.1; BAD97132.1; AAH14636.1; AAP36024.1; CAA74749.2 

Protein Name

 Putative GTP-binding protein 6 

Protein Synonyms/Alias

 Pseudoautosomal GTP-binding protein-like 

Gene Name

 GTPBP6 

Gene Synonyms/Alias

 PGPL 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
155	DRKLIFGKGNFEHLT	ubiquitination	[1, 2]
312	CGKTTLIKALTGDAA	ubiquitination	[3]
393	HPEAELQKCSVLSTL	ubiquitination	[3]
457	ELDAAVLKATGRQIL	ubiquitination	[3]
509	ISNSAYGKFRKLFPG	ubiquitination	[1, 2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

 DOMAIN 306 391 G.
 NP_BIND 301 309 GTP (By similarity).  

Keyword

 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 516 AA 

Protein Sequence

Gene Ontology

 GO:0005525; F:GTP binding; TAS:ProtInc. 

Interpro

 IPR006073; GTP_binding_domain.
 IPR016496; GTPase_HflX.
 IPR027417; P-loop_NTPase. 

Pfam

 PF01926; MMR_HSR1 

SMART

  

PROSITE

  

PRINTS