CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040303
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 NEDD8-conjugating enzyme Ubc12 
Protein Synonyms/Alias
  
Gene Name
 Ube2m 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
32CPDEGFYKSGKFVFSubiquitination[1]
35EGFYKSGKFVFSFKVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Ligase; Reference proteome; Ubl conjugation pathway. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 172 AA 
Protein Sequence
XNLPKTCDIS FSDPDDLLNF KLVICPDEGF YKSGKFVFSF KVGQGYPHDP PKVKCETMVY 60
HPNIDLEGNV CLNILREDWK PVLTINSIIY GLQYLFLVSR VRHLKLRVCW PSASLLPVDF 120
HLYRPQEPNP EDPLNKEAAE VLQNNRRLFE QNVQRSMRGG YIGSTYFERC LK 172 
Gene Ontology
 GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro. 
Interpro
 IPR000608; UBQ-conjugat_E2.
 IPR023313; UBQ-conjugating_AS.
 IPR016135; UBQ-conjugating_enzyme/RWD. 
Pfam
 PF00179; UQ_con 
SMART
  
PROSITE
 PS00183; UBIQUITIN_CONJUGAT_1
 PS50127; UBIQUITIN_CONJUGAT_2 
PRINTS