CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029303
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ76254, highly similar to Homo sapiens gamma-glutamyl hydrolase (GGH), mRNA 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
212TMNEKLKKFFNVLTTubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Hydrolase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 318 AA 
Protein Sequence
MASPGRLLCV LGLLLCGAAS LELSRPHGDT TKKPIIGILM QKCRNKVMKN YGRYYIAASY 60
VKYLESAGAR VVPVRLDLTE KDYEILFKSI NGILFPGGSV DLRRSDYAKV AKIFYNLSIQ 120
SFDDGDYFPV WGTCLGFEEL SLLISGECLL TATDTVDVAM PLNFTGGQLH SRMFQNFPTE 180
LLLSLAVEPL TANFHKWSLS VKNFTMNEKL KKFFNVLTTN TDGKIEFIST MEGYKYPVYG 240
VQWHPEKAPY EWKNLDGISH APNAVKTAFY LAEFFVNEAR KNNHHFKSES EEEKALIYQF 300
SPIYTGNISS FQQCYIFD 318 
Gene Ontology
 GO:0008242; F:omega peptidase activity; IEA:InterPro.
 GO:0006541; P:glutamine metabolic process; IEA:InterPro. 
Interpro
 IPR015527; Pept_C26_g-glut_hydrolase.
 IPR011697; Peptidase_C26. 
Pfam
 PF07722; Peptidase_C26 
SMART
  
PROSITE
 PS51275; PEPTIDASE_C26_GGH 
PRINTS