UniProt Accession

 Q3U1Q4_MOUSE; Q3U1Q4 

Genbank Protein ID

 AK155800 

Genbank Nucleotide ID

 BAE33439.1 

Protein Name

 Putative uncharacterized protein 

Protein Synonyms/Alias

  

Gene Name

 Grb2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
10	AIAKYDFKATADDEL	ubiquitination	[1]
109	GNDVQHFKVLRDGAG	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 SH3 domain. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 217 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005886; C:plasma membrane; IDA:MGI.
 GO:0012506; C:vesicle membrane; IDA:MGI.
 GO:0005070; F:SH3/SH2 adaptor activity; IDA:MGI.
 GO:0048646; P:anatomical structure formation involved in morphogenesis; IMP:MGI.
 GO:0060670; P:branching involved in labyrinthine layer morphogenesis; IMP:MGI.
 GO:0030154; P:cell differentiation; IMP:MGI.
 GO:0030838; P:positive regulation of actin filament polymerization; IGI:MGI.
 GO:0007265; P:Ras protein signal transduction; TAS:MGI.
 GO:0043408; P:regulation of MAPK cascade; IGI:MGI. 

Interpro

 IPR000108; p67phox.
 IPR000980; SH2.
 IPR001452; SH3_domain. 

Pfam

 PF00017; SH2
 PF00018; SH3_1 

SMART

 SM00252; SH2
 SM00326; SH3 

PROSITE

 PS50001; SH2
 PS50002; SH3 

PRINTS

 PR00499; P67PHOX.
 PR00401; SH2DOMAIN.
 PR00452; SH3DOMAIN.