CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041822
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sodium/hydrogen exchanger 
Protein Synonyms/Alias
  
Gene Name
 Slc9a3 
Gene Synonyms/Alias
 mCG_20958 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
512FDRKFLSKVLMRRSAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Antiport; Complete proteome; Ion transport; Membrane; Reference proteome; Sodium; Sodium transport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 829 AA 
Protein Sequence
MWHRALGPGW KLLLALALTS LQGARGAEEE PSSDGSFQVV TFKWHHVQDP YIIALWILVA 60
SLAKIVFHLS HKVTSIVPES ALLIVLGLVL GGIVWAADHI ASFTLTPTLF FFYLLPPIVL 120
DAGYFMPNRL FFGNLGTILL YAVIGTIWNA ATTGLSLYGV FLSGLMGELK IGLLDFLLFG 180
SLIAAVDPVA VLAVFEEVHV NEVLFIIVFG ESLLNDAVTV VLYNVFESFV TLGGDAVTGV 240
DCVKGIVSFF VVSLGGTLVG VIFAFLLSLV TRFTKHVRII EPGFVFVISY LSYLTSEMLS 300
LSSILAITFC GICCQKYVKA NISEQSATTV RYTMKMLASG AETIIFMFLG ISAVNPDIWT 360
WNTAFVLLTL VFISVYRAIG VVLQTWILNR YRMVQLETID QVVMSYGGLR GAVAYALVVL 420
LDEKKVKEKN LFVSTTLIVV FFTVIFQGLT IKPLVQWLKV KRSEHREPKL NEKLHGRAFD 480
HILSAIEDIS GQIGHNYLRD KWSNFDRKFL SKVLMRRSAQ KSRDRILNVF HELNLKDAIS 540
YVAEGERRGS LAFIRSPSTD NMVNVDFNTP RPSTVEASVS YFLRENVSAV CLDMQSLEQR 600
RRSIRDTEDM VTHHTLQQYL YKPRQEYKHL YSRHELTPNE DEKQDKEIFH RTMRKRLESF 660
KSAKLGINQN KKAAKLYKRE RAQKRRNSSI PNGKLPMENL AHNYTIKEKD LELSEHEEAT 720
NYEEISGGIE FLASVTQDVA SDSGAGIDNP VFSPDEDLDP SILSRVPPWL SPGETVVPSQ 780
RARVQIPNSP SNFRRLTPFR LSNKSVDSFL QADGHEEQLQ PAAPESTHM 829 
Gene Ontology
 GO:0016324; C:apical plasma membrane; IDA:MGI.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0015385; F:sodium:hydrogen antiporter activity; IDA:MGI.
 GO:0006885; P:regulation of pH; IDA:MGI. 
Interpro
 IPR006153; Cation/H_exchanger.
 IPR018422; Cation/H_exchanger_CPA1.
 IPR018410; Na/H_exchanger_3/5.
 IPR004709; NaH_exchanger.
 IPR011256; Reg_factor_effector_bac. 
Pfam
 PF00999; Na_H_Exchanger 
SMART
  
PROSITE
  
PRINTS
 PR01084; NAHEXCHNGR.
 PR01087; NAHEXCHNGR3.