CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041257
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 NMDA receptor regulated 2, isoform CRA_a 
Protein Synonyms/Alias
 NMDA receptor-regulated protein 2 
Gene Name
 NARG2 
Gene Synonyms/Alias
 hCG_2004402 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
3*****MKKHVNEEVTubiquitination[1]
22FLQNSAKKCAQDYNMubiquitination[1]
40DARLFTEKILRACIEubiquitination[1, 2]
89LLALGSVKYVKTVFPubiquitination[2, 3]
211IFHEVPLKFMMSKNTubiquitination[1]
331MEQLQKEKQLVTGMDubiquitination[1]
803LDTTTQQKIGGTRMPubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Receptor; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 845 AA 
Protein Sequence
MKKHVNEEVT EFLKFLQNSA KKCAQDYNML SDDARLFTEK ILRACIEQVK KYSEFYTLHE 60
VTSLMGFFPF RVEMGLKLEK TLLALGSVKY VKTVFPSMPI KLQLSKDDIA TIETSEQTAE 120
AMHYDISKDP NAEKLVSRYH PQIALTSQSL FTLLNNHGPT YKEQWEIPVC IQVIPVAGSK 180
PVKVIYINSP LPQKKMTMRE RNQIFHEVPL KFMMSKNTSV PVSAVFMDKP EEFISEMDMS 240
CEVNECRKIE SLENLYLDFD DDVTELETFG VTTTKVSKSP SPASTSTVPN MTDAPTAPKA 300
GTTTVAPSAP DISANSRSLS QILMEQLQKE KQLVTGMDGG PEECKNKDDQ GFESCEKVSN 360
SDKPLIQDSD LKTSDALQLE NSQEIETSNK NDMTIDILHA DGERPNVLEN LDNSKEKTVG 420
SEAAKTEDTV LCSSDTDEEC LIIDTECKNN SDGKTAVVGS NLSSRPASPN SSSGQASVGN 480
QTNTACSPEE SCVLKKPIKR VYKKFDPVGE ILKMQDELLK PISRKVPELP LMNLENSKQP 540
SVSEQLSGPS DSSSWPKSGW PSAFQKPKGR LPYELQDYVE DTSEYLAPQE GNFVYKLFSL 600
QDLLLLVRCS VQRIETRPRS KKRKKIRRQF PVYVLPKVEY QACYGVEALT ESELCRLWTE 660
SLLHSNSSFY VGHIDAFTSK LFLLEEITSE ELKEKLSALK ISNLFNILQH ILKKLSSLQE 720
GSYLLSHAAE DSSLLIYKAS DGKVTRTAYN LYKTHCGLPG VPSSLSVPWV PLDPSLLLPY 780
HIHHGRIPCT FPPKSLDTTT QQKIGGTRMP TRSHRNPVSM ETKSSCLPAQ QVETEGVAPH 840
KRKIT 845 
Gene Ontology
 GO:0005634; C:nucleus; IEA:Compara. 
Interpro
 IPR019535; NARG2_C. 
Pfam
 PF10505; NARG2_C 
SMART
  
PROSITE
  
PRINTS