CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043996
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 
Protein Synonyms/Alias
  
Gene Name
 HBP1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
217GTRLCFHKGSNKEWQubiquitination[1]
221CFHKGSNKEWQDVEDubiquitination[1]
247DLQMGIHKGYGSDGLubiquitination[1]
289GLLTVECKLDHPFYVubiquitination[1]
390FARSGFSKNCGSPGSubiquitination[1, 2]
408SSNSLYAKAVKNHSSubiquitination[1]
411SLYAKAVKNHSSGTVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 454 AA 
Protein Sequence
QMPNAVQKLL LVMDKRASGM NDSLELLQCN ENLPSSPGYN SCDEHMELDD LPELQAVQSD 60
PTQSGMYQLS SDVSHQEYPR SSWNQNTSDI PETTYRENEV DWLTELANIA TSPQSPLMQC 120
SFYNRSSPVH IIATSKSLHS YARPPPVSSS SKSEPAFPHH HWKEETPVRH ERANSESESG 180
IFCMSSLSDD DDLGWCNSWP STVWHCFLKG TRLCFHKGSN KEWQDVEDFA RAEGCDNEED 240
LQMGIHKGYG SDGLKLLSHE ESVSFGESVL KLTFDPGTVE DGLLTVECKL DHPFYVKNKG 300
WSSFYPSLTV VQHGIPCCEV HIGDVCLPPG HPDAINFDDS GVFDTFKSYD FTPMDSSAVY 360
VLSSMARQRR ASLSCGGPGG QDFARSGFSK NCGSPGSSQL SSNSLYAKAV KNHSSGTVSA 420
TSPNKCKRPM NAFMLFAKKY RVEYTQMYPG KDNR 454 
Gene Ontology
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0043268; P:positive regulation of potassium ion transport; IEA:Compara. 
Interpro
 IPR013723; Ataxin-1_HBP1.
 IPR003652; Ataxin_AXH_dom.
 IPR009071; HMG_box_dom. 
Pfam
 PF08517; AXH 
SMART
 SM00536; AXH 
PROSITE
 PS51148; AXH 
PRINTS