CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038507
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 ATP-binding cassette sub-family A member 7 
Protein Synonyms/Alias
  
Gene Name
 Abca7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1807QERERVTKGATQGDVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2167 AA 
Protein Sequence
MALGTQLMLL LWKNYTYRRR QPIQLLVELL WPLFLFFILV AVRHSHPPLE HHECHFPNKP 60
LPSAGTVPWL QGLVCNVNNS CFQHPTPGEK PGVLSNFKDS LISRLLADTR TVLGGHSIQD 120
MLDALGKLIP VLRAVGGGAR PQESDQPTSQ GSVTKLLEKI LQRASLDPVL GQAQDSMRKF 180
SDAIRDLAQE LLTLPSLMEL RALLRRPRGS AGSLELVSEA LCSTKGPSSP GGLSLNWYEA 240
NQLNEFMGPE VAPALPDNSL SPACSEFVGT LDDHPVSRLL WRRLKPLILG KILFAPDTNF 300
TRKLMAQVNQ TFEELALLRD LHELWGVLGP QIFNFMNDST NVAMLQRLLD VGGTGQRQQT 360
PRAQKKLEAI KDFLDPSRGG YSWREAHADM GRLAGILGQM MECVSLDKLE AVPSEEALVS 420
RALELLGERR LWAGIVFLSP EHPLDPSELS SPALSPGHLR FKIRMDIDDV TRTNKIRDKF 480
WDPGPSADPF MDLRYVWGGF VYLQDLLEQA AVRVLGGGNS RTGLYLQQMP HPCYVDDVFL 540
RVLSRSLPLF LTLAWIYSVA LTVKAVVREK ETRLRETMRA MGLSRAVLWL GWFLSCLGPF 600
LVSAALLVLV LKLGNILPYS HPVVIFLFLA AFAVATVAQS FLLSAFFSRA NLAAACGGLA 660
YFALYLPYVL CVAWRERLHL GGLLAASLLS PVAFGFGCES LALLEEQGDG AQWHNLGTGP 720
AEDVFSLAQV SAFLLLDAVI YGLALWYLEA VCPGQYGIPE PWNFPFRRSY WCGPGPPKSS 780
VLAPAPQDPK VLVEEPPLGL VPGVSIRGLK KHFRGCPQPA LQGLNLDFYE GHITAFLGHN 840
GAGKTTTLSI LSGLFPPSSG SASILGHDVQ TNMAAIRPHL GICPQYNVLF DMLTVEEHVW 900
FYGRLKGVSA AAMGPERERL IRDVGLTLKR DTQTRHLSGG MQRKLSVAIA FVGGSRVVIM 960
DEPTAGVDPA SRRGIWELLL KYREGRTLIL STHHLDEAEL LGDRVAMVAG GSLCCCGSPL 1020
FLRRHLGCGY YLTLVKSSQS LVTHDAKGDS EDPRREKKSD GNGRTSDTAF TRGTSDKSNQ 1080
APAPGAVPIT PSTARILELV QQHVPGAQLV EDLPHELLLV LPYAGALDGS FAMVFQELDQ 1140
QLELLGLTGY GISDTNLEEI FLKVVEDAHR EGGDSRPQLH LRTCTPQPPT GPEASVLENG 1200
ELAKLVLDPQ APQGLAPNAA QVQGWTLTCQ QLRALLHKRF LLARRSRRGL FAQVVLPALF 1260
VGLALFFSLI VPPFGQYPPL QLSPAMYGPQ VSFFSEDAPG DPNRMKLLEA LLGEAGLQEP 1320
SMQDKDARGS ECTHSLACYF TVPEVPPDVA SILASGNWTP ESPSPACQCS QPGARRLLPD 1380
CPAGAGGPPP PQAVAGLGEV VQNLTGRNVS DFLVKTYPSL VRRGLKTKKW VDEVRYGGFS 1440
LGGRDPDLPT GHEVVRTLAE IRALLSPQPG NALDRILNNL TQWALGLDAR NSLKIWFNNK 1500
GWHAMVAFVN RANNGLLHAL LPSGPVRHAH SITTLNHPLN LTKEQLSEAT LIASSVDVLV 1560
SICVVFAMSF VPASFTLVLI EERITRAKHL QLVSGLPQTL YWLGNFLWDM CNYLVAVCIV 1620
VFIFLAFQQR AYVAPENLPA LLLLLLLYGW SITPLMYPAS FFFSVPSTAY VVLTCINLFI 1680
GINSSMATFV LELLSDQNLQ EVSRILKQVF LIFPHFCLGR GLIDMVRNQA MADAFERLGD 1740
KQFQSPLRWD IIGKNLLAMM AQGPLFLLIT LLLQHRNRLL PQSKPRLLPP LGEEDEDVAQ 1800
ERERVTKGAT QGDVLVLRDL TKVYRGQRNP AVDRLCLGIP PGECFGLLGV NGAGKTSTFR 1860
MVTGDTLPSS GEAVLAGHNV AQERSAAHRS MGYCPQSDAI FDLLTGREHL ELFARLRGVP 1920
EAQVAQTALS GLVRLGLPSY ADRPAGTYSG GNKRKLATAL ALVGDPAVVF LDEPTTGMDP 1980
SARRFLWNSL LSVVREGRSV VLTSHSMEEC EALCTRLAIM VNGRFRCLGS SQHLKGRFGA 2040
GHTLTLRVPP DQPEPAIAFI RITFPGAELR EVHGSRLRFQ LPPGGRCTLT RVFRELAAQG 2100
RAHGVEDFSV SQTTLEEVFL YFSKDQGEEE ESSRQEAEEE EVSKPGRQHP KRVSRFLEDP 2160
SSVETMI 2167 
Gene Ontology
 GO:0016324; C:apical plasma membrane; IDA:MGI.
 GO:0005622; C:intracellular; IDA:MGI.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:InterPro.
 GO:0005548; F:phospholipid transporter activity; IDA:MGI.
 GO:0006200; P:ATP catabolic process; IEA:GOC.
 GO:0033700; P:phospholipid efflux; IDA:MGI. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR026082; ABC_A.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS